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2-Methoxypyrimidine-5-carbonitrile
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2-Methoxypyrimidine-5-carbonitrile
Artikel-Nr:
(BOSSBS-5018R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5018R-A647
Lokale Artikelnummer::
BOSSBS-5018R-A647
Beschreibung:
ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7883R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7883R-A647
Lokale Artikelnummer::
BOSSBS-7883R-A647
Beschreibung:
Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7717R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7717R-A680
Lokale Artikelnummer::
BOSSBS-7717R-A680
Beschreibung:
Regulator of sister chromatid cohesion in mitosis stabilising cohesin complex association with chromatin. May antagonise the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0646R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0646R-A750
Lokale Artikelnummer::
BOSSBS-0646R-A750
Beschreibung:
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4282R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4282R-A750
Lokale Artikelnummer::
BOSSBS-4282R-A750
Beschreibung:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6757R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6757R-A350
Lokale Artikelnummer::
BOSSBS-6757R-A350
Beschreibung:
The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5562R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5562R-A488
Lokale Artikelnummer::
BOSSBS-5562R-A488
Beschreibung:
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3103R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3103R-A350
Lokale Artikelnummer::
BOSSBS-3103R-A350
Beschreibung:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9524R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9524R-A555
Lokale Artikelnummer::
BOSSBS-9524R-A555
Beschreibung:
PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, increased tendency to venous thrombosis, and variable degrees of bone marrow failure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12419R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12419R-A750
Lokale Artikelnummer::
BOSSBS-12419R-A750
Beschreibung:
Adapter protein implicated in the regulation of a large spectrum of both general and specialised Signalling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0735R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0735R-A488
Lokale Artikelnummer::
BOSSBS-0735R-A488
Beschreibung:
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1133R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1133R-A647
Lokale Artikelnummer::
BOSSBS-1133R-A647
Beschreibung:
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6735R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6735R-A647
Lokale Artikelnummer::
BOSSBS-6735R-A647
Beschreibung:
SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8615R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8615R-A555
Lokale Artikelnummer::
BOSSBS-8615R-A555
Beschreibung:
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0519R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0519R-A647
Lokale Artikelnummer::
BOSSBS-0519R-A647
Beschreibung:
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6586R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6586R-A488
Lokale Artikelnummer::
BOSSBS-6586R-A488
Beschreibung:
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. Tissue specificity; Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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