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Strontiumperchlorat+Trihydrat
Artikel-Nr:
(PRSI5155P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5155P
Lokale Artikelnummer::
PRSI5155P
Beschreibung:
beta-Galactosidase peptide is used for blocking the activity of b-galactosidase antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3321)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3321
Lokale Artikelnummer::
PRSI3321
Beschreibung:
PIKE Antibody: Phosphoinositide 3 kinase enhancer (PIKE) is a recently identified nuclear GTPase that interacts with nuclear phosphoinositide 3-kinase (PI3 kinase) to stimulate its lipid kinase activity. PIKE exists in multiple isoforms; a shorter C-terminal isoform (PIKE-A) has also been identified as centaurin gamma 1. The longest isoform (PIKE-L) has been shown to bind to the adaptor protein Homer and thereby link to metabotropic glutamate receptors, leading to activation of PI3 kinase activity and prevention of neuronal apoptosis. Overexpression of PIKE-A enhances Akt activity and promotes cancer cell invasion, whereas decreased expression of PIKE-A via dominant negative expression of PIKE-A or PIKE-A knockdown inhibits these processes. In many human cancers, expression of PIKE-A is enhanced, leading to increased Akt activity and preventing apoptosis.
VE:
1 * 100 µG
Lieferant:
ACROBIOSYSTEMS
Beschreibung:
Human recombinant integrin alpha M beta 2 (from HEK293 cells)
Lieferant:
ACROBIOSYSTEMS
Beschreibung:
Human recombinant integrin alpha 8 beta 1 (from HEK293)
Artikel-Nr:
(ABNOPAB10406)
Lieferant:
Abnova
Hersteller-Artikelnummer::
PAB10406
Lokale Artikelnummer::
ABNOPAB10406
Beschreibung:
Sheep polyclonal antibody raised against synthetic peptide of SR beta.
VE:
1 * 250 µG
Artikel-Nr:
(BSBTMA1111)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
MA1111
Lokale Artikelnummer::
BSBTMA1111
Beschreibung:
Mouse IgG monoclonal antibody for beta-HCG, chorionic gonadotropin, beta polypeptide (CGB) detection. Tested with IHC-P in Human. No cross reactivity with other proteins.
VE:
1 * 0,1 mg
Artikel-Nr:
(PRSI3521)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3521
Lokale Artikelnummer::
PRSI3521
Beschreibung:
IRS-1 Antibody: Following tyrosine phosphorylation, the insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) can form a protein scaffolding for the assembly of a host of Src homology 2 (SH2) domain-containing proteins. IRS-1 tyrosine phosphorylation can occur through the activity of several cytokine and growth factor receptors such as interleukin (IL)-4, IL-9, interferon-gamma, in addition to the insulin and insulin-like growth factor 1 receptors. The scaffolding provided by IRS-1 and IRS-2 is necessary for insulin signal transduction across the cell membrane. IRS-1 tyrosine phosphorylation, and thus formation of the IRS scaffolding is inhibited by tumor necrosis factor (TNF), and this inhibition can itself be blocked by rapamycin, an inhibitor of the mammalian target of rapamycin (TOR). TNF activity could also be blocked by inhibition of the Akt kinase and the PTEN tumor suppressor, suggesting that TNF impairs insulin signaling through IRS-1 by activation of the TOR signaling pathway.
VE:
1 * 100 µG
Artikel-Nr:
(ICNA0856030)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0856030
Lokale Artikelnummer::
ICNA0856030
Beschreibung:
Anti-beta-galactosidase Goat Polyclonal Antibody
VE:
1 * 2 mL
Artikel-Nr:
(APOSOR470584-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR470584-1G
Lokale Artikelnummer::
APOSOR470584-1G
Beschreibung:
Methyl 1-Methyl-7-indolecarboxylate
VE:
1 * 1 g
Artikel-Nr:
(PRSI90-400)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-400
Lokale Artikelnummer::
PRSI90-400
Beschreibung:
CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be up-regulated through interferon-gamma. B7-1 and B7-2 are both members of the immunoglobulin superfamily. It has been observed that both human and mouse B7-1 and B7-2 can bind to either human or mouse CD28 and CTLA-4, suggesting that there are conserved amino acids which form the B7-1/B7-2/CD28/CTLA-4 critical binding sites.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-4107R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4107R-A647
Lokale Artikelnummer::
BOSSBS-4107R-A647
Beschreibung:
Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface.
VE:
1 * 100 µl
Lieferant:
ACROBIOSYSTEMS
Beschreibung:
Biotinylated Human TGF-beta RII / TGFBR2 Protein, His,Avitag™.
Artikel-Nr:
(APOSPC6122D-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC6122D-1G
Lokale Artikelnummer::
APOSPC6122D-1G
Beschreibung:
Methyl perfluoro(2-methyl-3-oxahexanoate) 97%
VE:
1 * 1 g
Artikel-Nr:
(BLEG581309)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
581309
Lokale Artikelnummer::
BLEG581309
Beschreibung:
Mouse recombinant IFN-beta (from 293E cells)
VE:
1 * 1 Pack.
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(APOSPC7994-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC7994-1G
Lokale Artikelnummer::
APOSPC7994-1G
Beschreibung:
Methyl-3-{[4-(trifluoromethyl)piperidino]methyl}benzenecarboxylate
VE:
1 * 1 g
Artikel-Nr:
(APOSOR200007-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR200007-1G
Lokale Artikelnummer::
APOSOR200007-1G
Beschreibung:
Methyl-2-{[(4-methoxybenzyl)amino]methyl}benzoate
VE:
1 * 1 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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