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PROSCI
Artikel-Nr:
(PRSI90-530)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-530
Lokale Artikelnummer::
PRSI90-530
Beschreibung:
Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the cloned 28 kDa glycoprotein that is related to the p35 chain of IL-12. IL-27 is expressed by monocytes, endothelial cells and dendritic cells. IL-27 binds to and signals through a heterodimeric receptor complex composed of WSX1 (TCCR) and gp130. Evidence suggests IL-27 interacts only with WSX-1. IL-27 has both anti- and proinflammatory properties. As an antiinflammatory, IL-27 seems to induce a general negative feedback program that limits T and NK-T cell activity. At the onset of infection, IL-27 induces an IL-12 receptor on naie CD4+ T cells, making them susceptible to subsequent IL-12 activity (and possible Th1 development). Notably, IL-12 family cytokines are both induced and inhibited by bacterial products. Microbes promote IL-27 secretion through TLR4, and also block IL-27 production via C5a induction.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-237)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-237
Lokale Artikelnummer::
PRSI30-237
Beschreibung:
The function remains known.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-937)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-937
Lokale Artikelnummer::
PRSI61-937
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI61-926)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-926
Lokale Artikelnummer::
PRSI61-926
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI22-910)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-910
Lokale Artikelnummer::
PRSI22-910
Beschreibung:
Anti-KBTBD7 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI28-327)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-327
Lokale Artikelnummer::
PRSI28-327
Beschreibung:
SMARCD3 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCD3 is part of the lar
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-584)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-584
Lokale Artikelnummer::
PRSI30-584
Beschreibung:
Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. SIGLEC12 is a member of the SIGLEC3-like subfamily of SIGLECs. SIGLEC12, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor.Western blots using four different antibodies against four unique regions of this protein target confirm the same apparent molecular weight in our tests.Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-222)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-222
Lokale Artikelnummer::
PRSI42-222
Beschreibung:
Anti-USP16 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI22-747)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-747
Lokale Artikelnummer::
PRSI22-747
Beschreibung:
Anti-HIST1H4A Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI76-416)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-416
Lokale Artikelnummer::
PRSI76-416
Beschreibung:
The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(PRSI76-814)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-814
Lokale Artikelnummer::
PRSI76-814
Beschreibung:
The FN50 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI33-648)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-648
Lokale Artikelnummer::
PRSI33-648
Beschreibung:
It recognises a protein of 15 kDa, identified as Gross cystic disease fluid protein 15 (GCDFP-15), also called Prolactin Inducible Protein, or PIP. It is a major protein component of benign breast gross cysts. It is a known marker of breast cancer, as it is found in approximately 50% of all breast cancer specimens. PIP is a prolactin and androgen controlled protein. This antibody is useful in the identification of metastatic breast carcinoma, or fluid analysis.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI62-155)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-155
Lokale Artikelnummer::
PRSI62-155
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI22-189)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-189
Lokale Artikelnummer::
PRSI22-189
Beschreibung:
Anti-PSG1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI61-179)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-179
Lokale Artikelnummer::
PRSI61-179
Beschreibung:
For WB starting dilution is: 1:2000.
VE:
1 * 200 µl
New Product
Artikel-Nr:
(PRSI62-969)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-969
Lokale Artikelnummer::
PRSI62-969
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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