PROSCI
Artikel-Nr:
(PRSI29-923)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-923
Lokale Artikelnummer::
PRSI29-923
Beschreibung:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI60-378)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-378
Lokale Artikelnummer::
PRSI60-378
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI3687)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3687
Lokale Artikelnummer::
PRSI3687
Beschreibung:
XBP-1 Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5797)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5797
Lokale Artikelnummer::
PRSI5797
Beschreibung:
ATG9B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-154)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-154
Lokale Artikelnummer::
PRSI25-154
Beschreibung:
ST18 repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. ST18 represses basal transcription activity from target promoters. ST18 inhibits colony formation in cultured breast cancer cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7001)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7001
Lokale Artikelnummer::
PRSI7001
Beschreibung:
RGS22 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11, 12, and 13 (GNA11, GNA12, and GNA13). While RGS22 has been postulated to play a role in spermiogenesis in the testis, it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis. Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells, suggesting that RGS22 may be a potential prognostic biomarker for metastasis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-645)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-645
Lokale Artikelnummer::
PRSI91-645
Beschreibung:
Ribose-Phosphate Pyrophosphokinase 2 (PRPS2) is a phosphoribosyl pyrophosphate synthetase that belongs to the ribose-phosphate pyrophosphokinase family. PRPS2 is a homodimer. The active form is probably an hexamer composed of three homodimers. PRPS2 catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. PRPS2 catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. In addition, PRPS2 plays a central role in the synthesis of purines and pyrimidines.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-796)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-796
Lokale Artikelnummer::
PRSI91-796
Beschreibung:
SELE is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. SELE functions as a cell-surface glycoprotein and has a role in immunoadhesion. In addition, SELE may also have a role in capillary morphogenesis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5803P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5803P
Lokale Artikelnummer::
PRSI5803P
Beschreibung:
USP10 peptide is used for blocking the activity of USP10 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5225P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5225P
Lokale Artikelnummer::
PRSI5225P
Beschreibung:
ZCRB1 peptide is used for blocking the activity of ZCRB1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-913)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-913
Lokale Artikelnummer::
PRSI28-913
Beschreibung:
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-731)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-731
Lokale Artikelnummer::
PRSI28-731
Beschreibung:
LDB1 is a transcriptional activator that associates with the LIM homeoproteins and coordinate transcription. LIM homeoproteins and LDBs are involved in a variety of developmental processes.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI23-890)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-890
Lokale Artikelnummer::
PRSI23-890
Beschreibung:
Anti-HIC1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI24-094)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-094
Lokale Artikelnummer::
PRSI24-094
Beschreibung:
Anti-NIP Recombinant Antibody [Clone: B1-8]
VE:
1 * 0,2 mg
Artikel-Nr:
(PRSI33-089)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-089
Lokale Artikelnummer::
PRSI33-089
Beschreibung:
This antibody recognises a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). The antibody recognises the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, Bcell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of Bcells and its expression is restricted to normal and neoplastic Bcells, being absent from all other leukocytes and tissues. It is expressed by pre Bcells and persists during all stages of Bcell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting Bcells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in Bcell activation and cell cycle progression.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-853)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-853
Lokale Artikelnummer::
PRSI61-853
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||