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PROSCI


28 361  results were found

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Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-668
Lokale Artikelnummer:: PRSI25-668
Beschreibung:   Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 71-204
Lokale Artikelnummer:: PRSI71-204
Beschreibung:   Anti-GLG1 Rabbit Polyclonal Antibody
VE:  1 * 50 µG
Artikel-Nr: (PRSI7283P)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 7283P
Lokale Artikelnummer:: PRSI7283P
Beschreibung:   17 amino acids near the carboxy terminus of human MTERFD2.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 35-280
Lokale Artikelnummer:: PRSI35-280
Beschreibung:   Anti-Influenza Goat Polyclonal Antibody (Biotin)
VE:  1 * 1 mL

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-293
Lokale Artikelnummer:: PRSI92-293
Beschreibung:   Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 63-749
Lokale Artikelnummer:: PRSI63-749
Beschreibung:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:  1 * 400 µl
New Product
Artikel-Nr: (PRSI45-156)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 45-156
Lokale Artikelnummer:: PRSI45-156
Beschreibung:   Anti-SYK Goat Polyclonal Antibody
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 27-873
Lokale Artikelnummer:: PRSI27-873
Beschreibung:   ZNF18 is a candidate transcription factor
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 4461
Lokale Artikelnummer:: PRSI4461
Beschreibung:   Slitrk3 Antibody: SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
VE:  1 * 100 µG
Artikel-Nr: (PRSI79-254)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-254
Lokale Artikelnummer:: PRSI79-254
Beschreibung:   Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 31-033
Lokale Artikelnummer:: PRSI31-033
Beschreibung:   PCNA is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 33-103
Lokale Artikelnummer:: PRSI33-103
Beschreibung:   CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesised MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. CD74 antibody stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. antibody to CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
VE:  1 * 100 µG
New Product

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 38-164
Lokale Artikelnummer:: PRSI38-164
Beschreibung:   Anti-DEFB103B Rabbit Polyclonal Antibody
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 3985
Lokale Artikelnummer:: PRSI3985
Beschreibung:   Nicastrin Antibody: Nicastrin, in addition to presenilin, PEN2, and APH-1 forms the gamma-secretase protein complex, a membrane-bound aspartyl protease that can cleave certain proteins at peptide bonds buried within the hydrophobic environment of the lipid bilayer. This cleavage is responsible for a key step in signaling from several cell-surface receptors and is thought to be required for the generation of the neurotoxic amyloid peptides that are central to the pathogenesis of Alzheimer's disease. Like the tumor necrosis factor-alpha-converting enzyme (TACE) and the beta-site cleavage enzyme (BACE) protease families, gamma-secretase will cleave the amyloid precursor protein (APP), but within the intramembrane region of APP, resulting in either the non-toxic p3 (from the alpha and gamma cleavage site) or the toxic Abeta amyloid peptide (from the beta and gamma cleavage site). It is thought that accumulation of the Abeta peptide is the precursor to Alzheimer's disease. Nicastrin is also thought to be involved in cell proliferation and signaling, especially in regards to activation of Notch receptors as loss of Nicastrin expression results in mouse embryonic lethality.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 35-185
Lokale Artikelnummer:: PRSI35-185
Beschreibung:   Anti-Feline Leukemia virus Goat Polyclonal Antibody
VE:  1 * 1 mL
Artikel-Nr: (PRSI42-392)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 42-392
Lokale Artikelnummer:: PRSI42-392
Beschreibung:   Anti-CNR1 Goat Polyclonal Antibody
VE:  1 * 100 µG
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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