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PROSCI
Artikel-Nr:
(PRSI2287)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2287
Lokale Artikelnummer::
PRSI2287
Beschreibung:
ASC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4). Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-473)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-473
Lokale Artikelnummer::
PRSI33-473
Beschreibung:
This antibody neutralises human TNFa mediated cytotoxicity of L929 cells and inhibits tumour growth in mice. It protects mice against toxicity of hTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI62-555)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-555
Lokale Artikelnummer::
PRSI62-555
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI33-361)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-361
Lokale Artikelnummer::
PRSI33-361
Beschreibung:
This mAb recognises a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B), or Elastase 3B. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI7045P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7045P
Lokale Artikelnummer::
PRSI7045P
Beschreibung:
KEAP1 peptide is used for blocking the activity of KEAP1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6213P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6213P
Lokale Artikelnummer::
PRSI6213P
Beschreibung:
Bcl9L peptide is used for blocking the activity of Bcl9L antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5191)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5191
Lokale Artikelnummer::
PRSI5191
Beschreibung:
OCLN Antibody: Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-535)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-535
Lokale Artikelnummer::
PRSI27-535
Beschreibung:
TFEC is an activator of transcription with two separate activation domains.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI23-423)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-423
Lokale Artikelnummer::
PRSI23-423
Beschreibung:
Anti-MT-ND5 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI19-667)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-667
Lokale Artikelnummer::
PRSI19-667
Beschreibung:
Anti-CBR1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI42-188)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-188
Lokale Artikelnummer::
PRSI42-188
Beschreibung:
Anti-SUMF1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI22-248)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-248
Lokale Artikelnummer::
PRSI22-248
Beschreibung:
Anti-POLE3 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI27-275)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-275
Lokale Artikelnummer::
PRSI27-275
Beschreibung:
KLF11 (TIEG2) is a pancreas-enriched transcription factor that has elicited significant attention because of its role as negative regulator of exocrine cell growth in vitro and in vivo. It plays a role in the regulation of pancreatic beta cell physiology, and its variants may contribute to the development of diabetes.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-974)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-974
Lokale Artikelnummer::
PRSI29-974
Beschreibung:
TYR is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. It catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-279)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-279
Lokale Artikelnummer::
PRSI33-279
Beschreibung:
Cluster of Differentiation 8 is a cell surface receptor expressed either as a heterodimer with the beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature Tcells and NK cells express CD8a. It binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in Tcell development and activation of mature Tcells. For mature Tcells, CD4 and 8 are mutually exclusive, so antibody to CD8 is generally used in conjunction with antibody to CD4.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI27-342)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-342
Lokale Artikelnummer::
PRSI27-342
Beschreibung:
GTF2E2 alpha's interaction with RNA polymerase II is subsequent to the entry of RNA polymerase II into the transcription cycle
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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