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PROSCI
Artikel-Nr:
(PRSI31-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-048
Lokale Artikelnummer::
PRSI31-048
Beschreibung:
MAPK14 encodes a protein which is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-671)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-671
Lokale Artikelnummer::
PRSI26-671
Beschreibung:
DPPA2 may play a role in maintaining cell pluripotentiality. ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-798)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-798
Lokale Artikelnummer::
PRSI26-798
Beschreibung:
The specific function of DENND2C is not yet known.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-999)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-999
Lokale Artikelnummer::
PRSI27-999
Beschreibung:
NPM1 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-802)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-802
Lokale Artikelnummer::
PRSI25-802
Beschreibung:
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like, ZO1-like, p55-like, and LIN2-like, based on their size and the presence of additional domains. MPP5 is a member of the p55-like MAGUK subfamily.Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001 [PubMed 11311936]). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-970)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-970
Lokale Artikelnummer::
PRSI25-970
Beschreibung:
TTYH1 is a member of the tweety family of proteins. Members of this family function as chloride anion channels. TTYH1 functions as a calcium (2+)-independent, volume-sensitive large conductance chloride (-) channel. This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium (2+)-independent, volume-sensitive large conductance chloride (-) channel. Two transcript variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-149)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-149
Lokale Artikelnummer::
PRSI45-149
Beschreibung:
Anti-SNAP25 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-524)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-524
Lokale Artikelnummer::
PRSI46-524
Beschreibung:
Anti-TRIM37 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-155)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-155
Lokale Artikelnummer::
PRSI36-155
Beschreibung:
Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse neutrophils in vivo.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-837)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-837
Lokale Artikelnummer::
PRSI27-837
Beschreibung:
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-315)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-315
Lokale Artikelnummer::
PRSI29-315
Beschreibung:
PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-893)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-893
Lokale Artikelnummer::
PRSI29-893
Beschreibung:
MTA2 modulates the enzymatic activity of the histone deacetylase core complex.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. This gene is found to be deleted in Williams syndrome.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI31-082)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-082
Lokale Artikelnummer::
PRSI31-082
Beschreibung:
PDCD4 is a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-679)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-679
Lokale Artikelnummer::
PRSI45-679
Beschreibung:
Anti-GRIK1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-402)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-402
Lokale Artikelnummer::
PRSI29-402
Beschreibung:
IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3559)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3559
Lokale Artikelnummer::
PRSI3559
Beschreibung:
CTRP2 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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