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PROSCI
Artikel-Nr:
(PRSI45-215)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-215
Lokale Artikelnummer::
PRSI45-215
Beschreibung:
Anti-AGRP Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI15-378)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
15-378
Lokale Artikelnummer::
PRSI15-378
Beschreibung:
Anti-SPDEF Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI79-775)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-775
Lokale Artikelnummer::
PRSI79-775
Beschreibung:
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity By similarity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6603P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6603P
Lokale Artikelnummer::
PRSI6603P
Beschreibung:
LEMD3 peptide is used for blocking the activity of LEMD3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4349P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4349P
Lokale Artikelnummer::
PRSI4349P
Beschreibung:
MANF peptide is used for blocking the activity of MANF antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-519)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-519
Lokale Artikelnummer::
PRSI35-519
Beschreibung:
Anti-Hepatitis C Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI96-166)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-166
Lokale Artikelnummer::
PRSI96-166
Beschreibung:
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI96-611)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-611
Lokale Artikelnummer::
PRSI96-611
Beschreibung:
Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4731P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4731P
Lokale Artikelnummer::
PRSI4731P
Beschreibung:
MED28 peptide is used for blocking the activity of MED28 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3663)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3663
Lokale Artikelnummer::
PRSI3663
Beschreibung:
TRAF2 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a NF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kappa B activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-801)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-801
Lokale Artikelnummer::
PRSI91-801
Beschreibung:
Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7385P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7385P
Lokale Artikelnummer::
PRSI7385P
Beschreibung:
18 amino acids near the center of human TRIM33.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7357P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7357P
Lokale Artikelnummer::
PRSI7357P
Beschreibung:
19 amino acid peptide near the amino terminus of human RNF20.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-198)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-198
Lokale Artikelnummer::
PRSI91-198
Beschreibung:
Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6521P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6521P
Lokale Artikelnummer::
PRSI6521P
Beschreibung:
ECRG1 peptide is used for blocking the activity of ECRG1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6169P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6169P
Lokale Artikelnummer::
PRSI6169P
Beschreibung:
LRRTM2 peptide is used for blocking the activity of LRRTM2 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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