PROSCI
Artikel-Nr:
(PRSI96-037)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-037
Lokale Artikelnummer::
PRSI96-037
Beschreibung:
AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI92-440)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-440
Lokale Artikelnummer::
PRSI92-440
Beschreibung:
Periostin is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumour suppressor. It is synthesised by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-051)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-051
Lokale Artikelnummer::
PRSI92-051
Beschreibung:
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
VE:
1 * 0,05 mg
New Product
Artikel-Nr:
(PRSI26-703)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-703
Lokale Artikelnummer::
PRSI26-703
Beschreibung:
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI64-159)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
64-159
Lokale Artikelnummer::
PRSI64-159
Beschreibung:
For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI26-050)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-050
Lokale Artikelnummer::
PRSI26-050
Beschreibung:
TSPAN6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI24-502)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-502
Lokale Artikelnummer::
PRSI24-502
Beschreibung:
Anti-IL6R Recombinant Antibody [Clone: rhPM-1 (Tocilizumab)]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI76-099)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-099
Lokale Artikelnummer::
PRSI76-099
Beschreibung:
The N418 monoclonal antibody specifically reacts with the integrin alpha x chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(PRSI24-414)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-414
Lokale Artikelnummer::
PRSI24-414
Beschreibung:
Anti-V alpha TCR Recombinant Antibody [Clone: 34]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI90-418)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-418
Lokale Artikelnummer::
PRSI90-418
Beschreibung:
CD152 and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulphide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4+ and CD8+ T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4+ T cells and 50% of CD8+ T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI60-943)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-943
Lokale Artikelnummer::
PRSI60-943
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI3321P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3321P
Lokale Artikelnummer::
PRSI3321P
Beschreibung:
PIKE peptide is used for blocking the activity of Anit-PIKE antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4299P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4299P
Lokale Artikelnummer::
PRSI4299P
Beschreibung:
PTK7 peptide is used for blocking the activity of PTK7 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI46-757)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-757
Lokale Artikelnummer::
PRSI46-757
Beschreibung:
Anti-SEPT7 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-225)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-225
Lokale Artikelnummer::
PRSI62-225
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI60-672)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-672
Lokale Artikelnummer::
PRSI60-672
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Preis auf Anfrage
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