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PROSCI
Artikel-Nr:
(PRSI2140)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2140
Lokale Artikelnummer::
PRSI2140
Beschreibung:
DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3587)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3587
Lokale Artikelnummer::
PRSI3587
Beschreibung:
Precerebellin Antibody: Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5729)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5729
Lokale Artikelnummer::
PRSI5729
Beschreibung:
APC6 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC6 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC6, it has been shown to interact with and is stabilized by CDC26 through an intermolecular TPR mimic composed of one helix from each protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI35-317)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-317
Lokale Artikelnummer::
PRSI35-317
Beschreibung:
Anti-Mycoplasma pneumoniae Rabbit Polyclonal Antibody
VE:
1 * 1 mL
Artikel-Nr:
(PRSI25-234)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-234
Lokale Artikelnummer::
PRSI25-234
Beschreibung:
RNF113B contains 1 RING-type zinc finger and 1 C3H1-type zinc finger and the function remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4993)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4993
Lokale Artikelnummer::
PRSI4993
Beschreibung:
KLRA3 Antibody: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6235)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6235
Lokale Artikelnummer::
PRSI6235
Beschreibung:
ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6455)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6455
Lokale Artikelnummer::
PRSI6455
Beschreibung:
DBX1 Antibody: DBX1 is implicated in patterning the central nervous system during embryogenesis. DBX1 homeodomain transcription factor is expressed in progenitors which are critical in establishing cell fate allocation and cell diversity. DBX1 has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. DBX1-derived neurons are essential for the transgenic expression and generation of respiratory behavior both in vitro and in vivo.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6985)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6985
Lokale Artikelnummer::
PRSI6985
Beschreibung:
BCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-216)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-216
Lokale Artikelnummer::
PRSI25-216
Beschreibung:
C16orf44 (KLHL36) probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-987)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-987
Lokale Artikelnummer::
PRSI25-987
Beschreibung:
Sulfatases, such as ARSH, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.Sulfatases, such as ARSH, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-591)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-591
Lokale Artikelnummer::
PRSI63-591
Beschreibung:
For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI63-893)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-893
Lokale Artikelnummer::
PRSI63-893
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI63-913)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-913
Lokale Artikelnummer::
PRSI63-913
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI64-022)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
64-022
Lokale Artikelnummer::
PRSI64-022
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI79-810)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-810
Lokale Artikelnummer::
PRSI79-810
Beschreibung:
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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