6,7-Dimethylchinolin-2,3-dicarbons\u00E4ure
Artikel-Nr:
(PRSI96-693)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-693
Lokale Artikelnummer::
PRSI96-693
Beschreibung:
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHPS1) is also known as CD172 antigen-like family member A (CD172a), Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha (SIRPA or SIRP alpha) or p84, is a member of the SIRP family, and also belongs to the immunoglobulin superfamily. SIRP alpha is Ubiquitous and highly expressed in brain. SIRPA / CD172a is immunoglobulin-like cell surface receptor for CD47 and acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPA / SHPS-1 supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment and may play a key role in intracellular signaling during synaptogenesis and in synaptic function By similarity. SIRPA / MyD1 involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin and mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
VE:
1 * 0,1 mg
Artikel-Nr:
(PRSI23-356)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-356
Lokale Artikelnummer::
PRSI23-356
Beschreibung:
Anti-POLR1D Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI71-296)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
71-296
Lokale Artikelnummer::
PRSI71-296
Beschreibung:
Anti-YES1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI23-623)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-623
Lokale Artikelnummer::
PRSI23-623
Beschreibung:
Anti-RIPK4 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI4227)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4227
Lokale Artikelnummer::
PRSI4227
Beschreibung:
Bub3 Antibody: The mitotic checkpoint protein Bub3 is involved with the essential spindle checkpoint pathway which operates during early embryogenesis. Bub3 is important during G2 and early mitosis stages, permitting entry into mitosis depending upon the assembly state of microtubules, thus preventing premature sister chromatid separation, mis-segregation and aneuploidy. Bub3 contains four WD repeat domains and is required for the kinetochore localization of Bub1, a related kinase that is necessary for spindle assembly checkpoint function. Bub1 is able to autophosphorylate and can catalyze the phosphorylation of Bub3. Both Bub1 and Bub3 are mutually dependent for function. Altered Bub expression levels may significantly impair mitotic checkpoint function and is associated with tumor cell proliferation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI96-313)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-313
Lokale Artikelnummer::
PRSI96-313
Beschreibung:
Fibroblast growth factor receptor 1 (FGFR1) is also known as basic fibroblast growth factor receptor 1(BFGFR1), FMS-like tyrosine kinase, CD331, and is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. This protein is one of several fibroblast growth factor receptors, which are related proteins that are involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and embryonic development.The FGFR1 protein spans the cell membrane, so that one end of the protein remains inside the cell and the other end projects from the outer surface of the cell. This positioning allows the FGFR1 protein to interact with specific growth factors outside the cell and to receive signals that help the cell respond to its environment. When growth factors attach to the FGFR1 protein, the receptor triggers a cascade of chemical reactions inside the cell that instruct the cell to undergo certain changes, such as maturing to take on specialized functions. The FGFR1 protein is thought to play an important role in the development of the nervous system. This protein may also help regulate the growth of long bones, such as the large bones in the arms and legs.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI48-641)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-641
Lokale Artikelnummer::
PRSI48-641
Beschreibung:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI62-429)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-429
Lokale Artikelnummer::
PRSI62-429
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI24-567)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-567
Lokale Artikelnummer::
PRSI24-567
Beschreibung:
Anti-CLEC4A Recombinant Antibody [Clone: 9E8]
VE:
1 * 0,2 mg
Artikel-Nr:
(PRSI30-749)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-749
Lokale Artikelnummer::
PRSI30-749
Beschreibung:
ZNF526 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 13 C2H2-type zinc fingers. ZNF526 may be involved in transcriptional regulation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI23-046)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-046
Lokale Artikelnummer::
PRSI23-046
Beschreibung:
Anti-C1GALT1C1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI62-500)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-500
Lokale Artikelnummer::
PRSI62-500
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI5567P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5567P
Lokale Artikelnummer::
PRSI5567P
Beschreibung:
SYNGR3 peptide is used for blocking the activity of SYNGR3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-140)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-140
Lokale Artikelnummer::
PRSI25-140
Beschreibung:
TEAD4 is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this protein.This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-285)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-285
Lokale Artikelnummer::
PRSI35-285
Beschreibung:
Purified IgG fraction of antiserum to a purity of >90%.
VE:
1 * 0,05 mL
Artikel-Nr:
(PRSI91-248)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-248
Lokale Artikelnummer::
PRSI91-248
Beschreibung:
Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).
VE:
1 * 50 µG
Preis auf Anfrage
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