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PROSCI
Artikel-Nr:
(PRSI45-248)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-248
Lokale Artikelnummer::
PRSI45-248
Beschreibung:
Anti-AIFM2 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-853)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-853
Lokale Artikelnummer::
PRSI25-853
Beschreibung:
RNF170 is a multi-pass membrane proteinPotential. It contains 1 RING-type zinc finger. The exact function of RNF170 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-910)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-910
Lokale Artikelnummer::
PRSI42-910
Beschreibung:
Anti-APOH Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7191)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7191
Lokale Artikelnummer::
PRSI7191
Beschreibung:
PTGDR2 Antibody: The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI96-595)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-595
Lokale Artikelnummer::
PRSI96-595
Beschreibung:
Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-477)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-477
Lokale Artikelnummer::
PRSI29-477
Beschreibung:
HNRPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein can act as a tetramer and is involved in the assembly of 40S hnRNP particles.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has one RRM domain that binds to RNAs. Two alternatively spliced transcript variants have been described for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4063P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4063P
Lokale Artikelnummer::
PRSI4063P
Beschreibung:
The peptide is used for blocking the activity of PDL-2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-031)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-031
Lokale Artikelnummer::
PRSI91-031
Beschreibung:
Mouse Interleukin-1 (IL-1) designates two proteins, IL-1 alpha and IL-1 beta , which are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-772)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-772
Lokale Artikelnummer::
PRSI29-772
Beschreibung:
C21orf7 plays a critical role in the TGF-beta signaling transduction pathway.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7325)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7325
Lokale Artikelnummer::
PRSI7325
Beschreibung:
CRTC2 Antibody: CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-153)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-153
Lokale Artikelnummer::
PRSI29-153
Beschreibung:
GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7593)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7593
Lokale Artikelnummer::
PRSI7593
Beschreibung:
Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation. Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells. IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-993)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-993
Lokale Artikelnummer::
PRSI25-993
Beschreibung:
TCTN3 may be involved in apoptosis regulation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI36-249)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-249
Lokale Artikelnummer::
PRSI36-249
Beschreibung:
ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI30-964)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-964
Lokale Artikelnummer::
PRSI30-964
Beschreibung:
The exact function of C10orf132 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-074)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-074
Lokale Artikelnummer::
PRSI31-074
Beschreibung:
CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
VE:
1 * 50 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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