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PROSCI


28 362  results were found

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Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 28-188
Lokale Artikelnummer:: PRSI28-188
Beschreibung:   In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 23-366
Lokale Artikelnummer:: PRSI23-366
Beschreibung:   Anti-AMY2A Rabbit Polyclonal Antibody
VE:  1 * 50 µl

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 38-103
Lokale Artikelnummer:: PRSI38-103
Beschreibung:   Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-443
Lokale Artikelnummer:: PRSI79-443
Beschreibung:   MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and themyogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite formyogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 28-887
Lokale Artikelnummer:: PRSI28-887
Beschreibung:   Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC1 also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
VE:  1 * 100 µG
Artikel-Nr: (PRSI45-073)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 45-073
Lokale Artikelnummer:: PRSI45-073
Beschreibung:   Anti-IRF8 Goat Polyclonal Antibody
VE:  1 * 100 µG
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 33-844
Lokale Artikelnummer:: PRSI33-844
Beschreibung:   Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-Factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 23-870
Lokale Artikelnummer:: PRSI23-870
Beschreibung:   Anti-FTCD Rabbit Polyclonal Antibody
VE:  1 * 50 µl
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 33-047
Lokale Artikelnummer:: PRSI33-047
Beschreibung:   The S100 family of proteins are found in vertebrates and are characterised by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 63-221
Lokale Artikelnummer:: PRSI63-221
Beschreibung:   For WB starting dilution is: 1:1000. For IF starting dilution is: 1:10~50. For IHC-P starting dilution is: 1:10~50.
VE:  1 * 400 µl
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-265
Lokale Artikelnummer:: PRSI92-265
Beschreibung:   Ferritin is a large, iron-storage heteropolymeric protein,which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin has oligomer of 24 subunits and two types of subunits including light chain(FTL) and heavy chain. Ferritin can remove Fe (Ⅱ) from solution in the presence of oxygen and is very important for iron homeostasis. Iron is absorbed in the ferrous form and deposited as ferric hydroxides after oxidation. Iron is first oxidised to the ferric state for storage as ferric oxyhdroxide whithin the protein shell of ferritin. Thus, ferritin removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms. Ferritin also plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 96-052
Lokale Artikelnummer:: PRSI96-052
Beschreibung:   Human recombinant Bace13 (from HEK293 cells)
VE:  1 * 200 µG
Artikel-Nr: (PRSI45-094)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 45-094
Lokale Artikelnummer:: PRSI45-094
Beschreibung:   Anti-MTA1 Goat Polyclonal Antibody
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 63-905
Lokale Artikelnummer:: PRSI63-905
Beschreibung:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:  1 * 400 µl

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 26-395
Lokale Artikelnummer:: PRSI26-395
Beschreibung:   The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 33-553
Lokale Artikelnummer:: PRSI33-553
Beschreibung:   This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognises human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
VE:  1 * 100 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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