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PROSCI


28 362  results were found

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Artikel-Nr: (PRSI27-379)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 27-379
Lokale Artikelnummer:: PRSI27-379
Beschreibung:   Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AHR ligands included a variety of aromatic hydrocarbons.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 91-772
Lokale Artikelnummer:: PRSI91-772
Beschreibung:   Brevican Core Protein (BCAN) is a secreted protein that belongs to the aggrecan/versican proteoglycan family. BCAN contains one C-type lectin domain, one EGF-like domain, one Ig-like V-type domain, one Sushi (CCP/SCR) domain and two Link domains. BCAN may play a role in the terminally differentiating and the adult nervous system during postnatal development. BCAN could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 29-227
Lokale Artikelnummer:: PRSI29-227
Beschreibung:   RBMS3 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2 (I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 29-364
Lokale Artikelnummer:: PRSI29-364
Beschreibung:   PPIE is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 29-939
Lokale Artikelnummer:: PRSI29-939
Beschreibung:   The SLC25 family is mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane. SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18.The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).
VE:  1 * 100 µG
Artikel-Nr: (PRSI79-194)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-194
Lokale Artikelnummer:: PRSI79-194
Beschreibung:   GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-876
Lokale Artikelnummer:: PRSI79-876
Beschreibung:   Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 23-260
Lokale Artikelnummer:: PRSI23-260
Beschreibung:   Anti-EYA3 Rabbit Polyclonal Antibody
VE:  1 * 50 µl

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 5549
Lokale Artikelnummer:: PRSI5549
Beschreibung:   NAT11 Antibody: N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE). Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-306
Lokale Artikelnummer:: PRSI25-306
Beschreibung:   ZNF471 belongs to the krueppel C2H2-type zinc-finger protein family. Itcontains 15 C2H2-type zinc fingers and 1 KRAB domain. ZNF471 may be involved in transcriptional regulation.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-999
Lokale Artikelnummer:: PRSI25-999
Beschreibung:   TMEM30B belongs to the CDC50/LEM3 family. It is a multi-pass membrane protein. The function of the TMEM30B protein remains unknown.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 3377
Lokale Artikelnummer:: PRSI3377
Beschreibung:   ECSIT Antibody: Activation of NF-kappa B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 4457
Lokale Artikelnummer:: PRSI4457
Beschreibung:   Slitrk2 Antibody: SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.
VE:  1 * 100 µG
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 33-849
Lokale Artikelnummer:: PRSI33-849
Beschreibung:   S100 belongs to the family of calcium binding proteins. S100 alpha and S100 beta proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S100A and S100B) but not on the alpha-chain of S100 (i.e. in S100A and S100A0). This antibody can be used to localize S100A and S100B in various tissue sections. S100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S100 protein.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 60-564
Lokale Artikelnummer:: PRSI60-564
Beschreibung:   For WB starting dilution is: 1:1000.
VE:  1 * 400 µl

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 63-446
Lokale Artikelnummer:: PRSI63-446
Beschreibung:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:  1 * 400 µl
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