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PROSCI
Artikel-Nr:
(PRSI92-061)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-061
Lokale Artikelnummer::
PRSI92-061
Beschreibung:
Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-543)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-543
Lokale Artikelnummer::
PRSI91-543
Beschreibung:
Protocadherin-10 (PCDH10) is a single-pass type I membrane protein that contains six extracellular cadherin domains, one transmembrane domain and one cytoplasmic tail differing from those of the classical cadherins. As a potential calcium-dependent cell-adhesion neuronal receptor, it may plays a role in the establishment and function of specific cell-cell connections in the brain. PCDH10 moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tested tissues.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-416)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-416
Lokale Artikelnummer::
PRSI26-416
Beschreibung:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-600)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-600
Lokale Artikelnummer::
PRSI35-600
Beschreibung:
Anti-Clostridum difficile Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-578)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-578
Lokale Artikelnummer::
PRSI27-578
Beschreibung:
SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-764)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-764
Lokale Artikelnummer::
PRSI45-764
Beschreibung:
Anti-IGFBP6 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6211)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6211
Lokale Artikelnummer::
PRSI6211
Beschreibung:
BAPX1 Antibody: BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-309)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-309
Lokale Artikelnummer::
PRSI79-309
Beschreibung:
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-274)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-274
Lokale Artikelnummer::
PRSI42-274
Beschreibung:
Anti-DIXDC1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-167)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-167
Lokale Artikelnummer::
PRSI27-167
Beschreibung:
COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-379)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-379
Lokale Artikelnummer::
PRSI27-379
Beschreibung:
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AHR ligands included a variety of aromatic hydrocarbons.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-772)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-772
Lokale Artikelnummer::
PRSI91-772
Beschreibung:
Brevican Core Protein (BCAN) is a secreted protein that belongs to the aggrecan/versican proteoglycan family. BCAN contains one C-type lectin domain, one EGF-like domain, one Ig-like V-type domain, one Sushi (CCP/SCR) domain and two Link domains. BCAN may play a role in the terminally differentiating and the adult nervous system during postnatal development. BCAN could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-227)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-227
Lokale Artikelnummer::
PRSI29-227
Beschreibung:
RBMS3 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2 (I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-364)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-364
Lokale Artikelnummer::
PRSI29-364
Beschreibung:
PPIE is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-939)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-939
Lokale Artikelnummer::
PRSI29-939
Beschreibung:
The SLC25 family is mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane. SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18.The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-194)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-194
Lokale Artikelnummer::
PRSI79-194
Beschreibung:
GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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