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PROSCI
Artikel-Nr:
(PRSI33-007)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-007
Lokale Artikelnummer::
PRSI33-007
Beschreibung:
Caspases, or cysteine-aspartic proteases, are a family of cysteine proteases that play essential roles in inflammation, apoptosis and necrosis. They are often referred to as the 'executioners of apoptosis.' Caspases are synthesised as inactive proenzymes comprising an N-terminal peptide (prodomain) together with one large and one small subunit. Active caspase-1 and -3 are heterodimers, containing two small and two large subunits. Active Caspase-3 subunits are 17 kD (p17) and 12 kD (p12). Pro Caspase-3 is inactive and has virtually no activity until it is cleaved by an initiator caspase. It is activated by Caspases -8, -9 and -10 ('initiator caspases') and then effects apoptosis by cleaving targeted cellular proteins.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI23-025)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-025
Lokale Artikelnummer::
PRSI23-025
Beschreibung:
Anti-FRK Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI19-360)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-360
Lokale Artikelnummer::
PRSI19-360
Beschreibung:
Anti-HMG20B Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI18-908)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
18-908
Lokale Artikelnummer::
PRSI18-908
Beschreibung:
Anti-MCM4 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI96-381)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-381
Lokale Artikelnummer::
PRSI96-381
Beschreibung:
Serpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 / HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 / HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2509)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2509
Lokale Artikelnummer::
PRSI2509
Beschreibung:
Caspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-081)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-081
Lokale Artikelnummer::
PRSI26-081
Beschreibung:
POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-033)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-033
Lokale Artikelnummer::
PRSI27-033
Beschreibung:
SGMS1 is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-036)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-036
Lokale Artikelnummer::
PRSI26-036
Beschreibung:
CEACAM4 belongs to the immunoglobulin superfamily.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-269)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-269
Lokale Artikelnummer::
PRSI30-269
Beschreibung:
NSDHL is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in NSDHL gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males.The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-749)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-749
Lokale Artikelnummer::
PRSI46-749
Beschreibung:
Anti-Clu Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-538)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-538
Lokale Artikelnummer::
PRSI61-538
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI62-642)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-642
Lokale Artikelnummer::
PRSI62-642
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI18-695)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
18-695
Lokale Artikelnummer::
PRSI18-695
Beschreibung:
Anti-RPS3 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI48-302)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-302
Lokale Artikelnummer::
PRSI48-302
Beschreibung:
GPR61 is an Orphan-A GPCR with an unknown ligand.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7349)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7349
Lokale Artikelnummer::
PRSI7349
Beschreibung:
DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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