STRATAGENE
Artikel-Nr:
(BOSSBS-13248R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-FITC
Lokale Artikelnummer::
BOSSBS-13248R-FITC
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(LAMA3970)
Lieferant:
LAMAPLAST
Hersteller-Artikelnummer::
3970
Lokale Artikelnummer::
LAMA3970
Beschreibung:
HDPE, natural.
VE:
1 * 1 ST
Artikel-Nr:
(SIAL161500-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
161500-5G
Lokale Artikelnummer::
SIAL161500-5G
Beschreibung:
5-Nitro-1,3-benzodioxol, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
MP Biomedicals
Beschreibung:
Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells.
Artikel-Nr:
(214-0093)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
1190/06M
Lokale Artikelnummer::
BIBB1190/06M
Beschreibung:
Pyrex® Borosilikatglas
VE:
1 * 50 ST
Artikel-Nr:
(BOSSBS-13202R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-A350
Lokale Artikelnummer::
BOSSBS-13202R-A350
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11604R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R
Lokale Artikelnummer::
BOSSBS-11604R
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(MOLD644101)
Lieferant:
MOLDEX
Hersteller-Artikelnummer::
644101
Lokale Artikelnummer::
MOLD644101
Beschreibung:
Twisters® earplugs have a soft foam pod for a comfortable, snug seal.
VE:
1 * 80 PAAR
Artikel-Nr:
(MOLEM39889137)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M39889137
Lokale Artikelnummer::
MOLEM39889137
Beschreibung:
Perfluoroctan
VE:
1 * 5 g
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Artikel-Nr:
(SERA10770.02)
Lieferant:
Serva
Hersteller-Artikelnummer::
10770.02
Lokale Artikelnummer::
SERA10770.02
Beschreibung:
Adenosin
VE:
1 * 25 g
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Lieferant:
FLUOROCHEM
Beschreibung:
2-Phenoxybenzaldehyd
Lieferant:
Brand
Beschreibung:
PP oder LDPE, hohl, mit Dichtringen und Vierkant- bzw. Achtkantgriffscheibe.
Artikel-Nr:
(BOSSBS-11604R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R-A488
Lokale Artikelnummer::
BOSSBS-11604R-A488
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11604R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R-FITC
Lokale Artikelnummer::
BOSSBS-11604R-FITC
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(PROOMM0458.00)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0458.00
Lokale Artikelnummer::
PROOMM0458.00
Beschreibung:
(-)-Chinin Hydrochlorid Dihydrat
VE:
1 * 500 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
(-)-Chinin Hydrochlorid Dihydrat, Sigma-Aldrich®
Preis auf Anfrage
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