Drucken
Lieferant:
Merck
Beschreibung:
Bariumtitanat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-3121R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3121R-A350
Lokale Artikelnummer::
BOSSBS-3121R-A350
Beschreibung:
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2518R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2518R-A750
Lokale Artikelnummer::
BOSSBS-2518R-A750
Beschreibung:
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0855R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0855R-FITC
Lokale Artikelnummer::
BOSSBS-0855R-FITC
Beschreibung:
Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBSM-0862M-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BSM-0862M-A680
Lokale Artikelnummer::
BOSSBSM-0862M-A680
Beschreibung:
Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Artikel-Nr:
(BOSSBS-4223R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4223R
Lokale Artikelnummer::
BOSSBS-4223R
Beschreibung:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4223R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4223R-CY5.5
Lokale Artikelnummer::
BOSSBS-4223R-CY5.5
Beschreibung:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11069R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11069R-A350
Lokale Artikelnummer::
BOSSBS-11069R-A350
Beschreibung:
Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11069R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11069R-FITC
Lokale Artikelnummer::
BOSSBS-11069R-FITC
Beschreibung:
Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked α (33-35 kDa) and β (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Lieferant:
Sartorius Balances
Beschreibung:
Die Cubis® II-Reihe ist modular aufgebaut, sodass der Kunde die Komponenten wählen kann, die für den gewünschten Anwendungsbereich am besten geeignet sind. Für den Kunden bedeutet dieses konfigurierbare Konzept qualifiziertes Wägen, gepaart mit einem hohen Maß an Flexibilität, ohne in teure Ausstattung mit speziellen Features investieren zu müssen, die unter Umständen gar nicht benötigt werden.
Artikel-Nr:
(BOSSBS-4107R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4107R-A647
Lokale Artikelnummer::
BOSSBS-4107R-A647
Beschreibung:
Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface.
VE:
1 * 100 µl
Artikel-Nr:
(USBI040255-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040255-BIOTIN
Lokale Artikelnummer::
USBI040255-BIOTIN
Beschreibung:
Anti-POLR2B Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(39455.A1)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
39455.A1
Lokale Artikelnummer::
ALFA39455.A1
Beschreibung:
Nickel naphthenate (5 - 12% Ni)
VE:
1 * 1 kg
Artikel-Nr:
(BOSSBS-8481R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8481R-HRP
Lokale Artikelnummer::
BOSSBS-8481R-HRP
Beschreibung:
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
|
Bitte warten Sie...Ihre Daten werden bearbeitet |
Listenansicht
