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Tetraphenylarsoniumchlorid+Monohydrat
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Tetraphenylarsoniumchlorid+Monohydrat
Artikel-Nr:
(BOSSBS-5287R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5287R-A488
Lokale Artikelnummer::
BOSSBS-5287R-A488
Beschreibung:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1112R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1112R-A750
Lokale Artikelnummer::
BOSSBS-1112R-A750
Beschreibung:
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome. (Also known as glypican 3; Intestinal protein OCI-5; GTR2-2; MXR7; Glypican-3 precursor).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2578R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2578R-A350
Lokale Artikelnummer::
BOSSBS-2578R-A350
Beschreibung:
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0244R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0244R-A350
Lokale Artikelnummer::
BOSSBS-0244R-A350
Beschreibung:
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9018R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9018R-A488
Lokale Artikelnummer::
BOSSBS-9018R-A488
Beschreibung:
Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0539R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0539R-A350
Lokale Artikelnummer::
BOSSBS-0539R-A350
Beschreibung:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3927R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3927R-A555
Lokale Artikelnummer::
BOSSBS-3927R-A555
Beschreibung:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10239R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10239R-A647
Lokale Artikelnummer::
BOSSBS-10239R-A647
Beschreibung:
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6920R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6920R-A750
Lokale Artikelnummer::
BOSSBS-6920R-A750
Beschreibung:
This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11649R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11649R-A488
Lokale Artikelnummer::
BOSSBS-11649R-A488
Beschreibung:
The NGG1 interacting factor 3-like 1 (NIF3L1) is a 377 amino acid protein expressed mainly in the cytoplasm of cells in several different tissues. It has been highly conserved throughout evolution, from bacteria to mammals. NIF3L participates in retinoic acid-primed neural differentiation of P19 embryonic carcinoma cells by cooperating with Trip15/CSN2, a transcriptional corepressor/component of COP9 signalosome. NIF3L1 interacts with itself and with the NIF3L1 binding protein 1 (NIF3L1 BP1), which is a novel protein presumed to contain a leucine zipper domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5550R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5550R-A647
Lokale Artikelnummer::
BOSSBS-5550R-A647
Beschreibung:
Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4989R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4989R-A647
Lokale Artikelnummer::
BOSSBS-4989R-A647
Beschreibung:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A647
Lokale Artikelnummer::
BOSSBS-6947R-A647
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4595R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4595R-A750
Lokale Artikelnummer::
BOSSBS-4595R-A750
Beschreibung:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3535R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3535R-A647
Lokale Artikelnummer::
BOSSBS-3535R-A647
Beschreibung:
PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6420R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6420R-A647
Lokale Artikelnummer::
BOSSBS-6420R-A647
Beschreibung:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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