Antikörper
Artikel-Nr:
(USBI040882-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040882-AP
Lokale Artikelnummer::
USBI040882-AP
Beschreibung:
Anti-RBM12 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIR9399-04A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
R9399-04A
Lokale Artikelnummer::
USBIR9399-04A
Beschreibung:
Anti-RPS6KA1 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBIC2572-40E-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2572-40E-HRP
Lokale Artikelnummer::
USBIC2572-40E-HRP
Beschreibung:
Anti-CDK2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Artikel-Nr:
(USBI129362)
Lieferant:
US Biological
Hersteller-Artikelnummer::
129362
Lokale Artikelnummer::
USBI129362
Beschreibung:
Anti-MAP1S Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-2170R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2170R-A647
Lokale Artikelnummer::
BOSSBS-2170R-A647
Beschreibung:
VWCE
VE:
1 * 100 µl
Artikel-Nr:
(USBI040303-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040303-FITC
Lokale Artikelnummer::
USBI040303-FITC
Beschreibung:
Anti-PPARG Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBI040556-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040556-HRP
Lokale Artikelnummer::
USBI040556-HRP
Beschreibung:
Anti-PSMB10 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-0087R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0087R-FITC
Lokale Artikelnummer::
BOSSBS-0087R-FITC
Beschreibung:
The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
VE:
1 * 100 µl
Artikel-Nr:
(ABGEAP3784F)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP3784F
Lokale Artikelnummer::
ABGEAP3784F
Beschreibung:
Anti-KIT Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(USBI036628-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
036628-FITC
Lokale Artikelnummer::
USBI036628-FITC
Beschreibung:
Anti-HLF Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBIR2032-50B)
Lieferant:
US Biological
Hersteller-Artikelnummer::
R2032-50B
Lokale Artikelnummer::
USBIR2032-50B
Beschreibung:
Anti-RLA, DR Mouse Monoclonal Antibody (Biotin) [clone: 5K114]
VE:
1 * 500 µG
Artikel-Nr:
(USBI031325)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031325
Lokale Artikelnummer::
USBI031325
Beschreibung:
Anti-VDR Mouse Monoclonal Antibody [clone: 517CT23.5.1]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11888R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11888R-A350
Lokale Artikelnummer::
BOSSBS-11888R-A350
Beschreibung:
MPPED2 (Metallophosphoesterase domain-containing protein 2), also known as C11orf8, FAM1B or 239FB, is a 294 amino acid protein. Expressed primarily in fetal brain tissue, MPPED2 is encoded by a gene that maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double stranded DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8312R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8312R-A750
Lokale Artikelnummer::
BOSSBS-8312R-A750
Beschreibung:
The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The FAM82A gene product has been provisionally designated FAM82A pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(USBI031476-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031476-AP
Lokale Artikelnummer::
USBI031476-AP
Beschreibung:
Anti-ABCC12 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-0534R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0534R-A488
Lokale Artikelnummer::
BOSSBS-0534R-A488
Beschreibung:
P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.
VE:
1 * 100 µl
Preis auf Anfrage
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