Antikörper
Artikel-Nr:
(BOSSBS-2413R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2413R-A647
Lokale Artikelnummer::
BOSSBS-2413R-A647
Beschreibung:
Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1997R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1997R-CY3
Lokale Artikelnummer::
BOSSBS-1997R-CY3
Beschreibung:
Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8541R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8541R-CY5
Lokale Artikelnummer::
BOSSBS-8541R-CY5
Beschreibung:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(USBIC2408-12B)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2408-12B
Lokale Artikelnummer::
USBIC2408-12B
Beschreibung:
Anti-CD53 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 5F45]
VE:
1 * 50 Tests
Artikel-Nr:
(BOSSBS-1616R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1616R-A350
Lokale Artikelnummer::
BOSSBS-1616R-A350
Beschreibung:
CAP2 is a identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15476R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15476R-CY3
Lokale Artikelnummer::
BOSSBS-15476R-CY3
Beschreibung:
HHIPL1.
VE:
1 * 100 µl
Artikel-Nr:
(USBI038661)
Lieferant:
US Biological
Hersteller-Artikelnummer::
038661
Lokale Artikelnummer::
USBI038661
Beschreibung:
Anti-MTL5 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-12394R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12394R-A555
Lokale Artikelnummer::
BOSSBS-12394R-A555
Beschreibung:
DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context; mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10056R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10056R-CY7
Lokale Artikelnummer::
BOSSBS-10056R-CY7
Beschreibung:
KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0123R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0123R-A488
Lokale Artikelnummer::
BOSSBS-0123R-A488
Beschreibung:
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K >neuromedin-K >substance P.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Artikel-Nr:
(BOSSBS-5308R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5308R-A350
Lokale Artikelnummer::
BOSSBS-5308R-A350
Beschreibung:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2522R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2522R-CY5
Lokale Artikelnummer::
BOSSBS-2522R-CY5
Beschreibung:
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11332R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11332R-A555
Lokale Artikelnummer::
BOSSBS-11332R-A555
Beschreibung:
Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12408R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12408R-CY5
Lokale Artikelnummer::
BOSSBS-12408R-CY5
Beschreibung:
Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNX10 (Sorting nexin-10) is a 201 amino acid protein that contains one phox domain and belongs to the SNX family. Like other members of the SNX family, SNX10 is thought to play a role in intracellular trafficking events throughout the cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0442R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0442R-A488
Lokale Artikelnummer::
BOSSBS-0442R-A488
Beschreibung:
ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.
VE:
1 * 100 µl
Preis auf Anfrage
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