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Antikörper
Artikel-Nr:
(USBI040530-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040530-PE
Lokale Artikelnummer::
USBI040530-PE
Beschreibung:
Anti-PRSSL1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI041173-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041173-BIOTIN
Lokale Artikelnummer::
USBI041173-BIOTIN
Beschreibung:
Anti-RPA1 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(USBI128484)
Lieferant:
US Biological
Hersteller-Artikelnummer::
128484
Lokale Artikelnummer::
USBI128484
Beschreibung:
Anti-ILK Mouse Monoclonal Antibody [clone: 4F10]
VE:
1 * 100 µG
Artikel-Nr:
(USBIC2252-03G)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2252-03G
Lokale Artikelnummer::
USBIC2252-03G
Beschreibung:
Anti-CD1C Mouse Monoclonal Antibody (Biotin) [clone: 7H208]
VE:
1 * 100 µG
Artikel-Nr:
(70-4031-U100)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
70-4031-U100
Lokale Artikelnummer::
TNBO70-4031-U100
Beschreibung:
The LTF-2 immunoglobulin is useful as an isotype-matched control. The LTF-2 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2b antibodies.
VE:
1 * 100 µG
Artikel-Nr:
(USBI040727-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040727-HRP
Lokale Artikelnummer::
USBI040727-HRP
Beschreibung:
Anti-QTRTD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-5170R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5170R
Lokale Artikelnummer::
BOSSBS-5170R
Beschreibung:
ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11498R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11498R-A680
Lokale Artikelnummer::
BOSSBS-11498R-A680
Beschreibung:
Olfactory sensory neurons contain olfactory receptors, which are G protein-coupled receptor proteins that localize to the cilia and display affinity for and bind to a variety of odor molecules. Olfactory neurons send their axons from the olfactory epithelium to the olfactory bulb, which is covered by the CNS basal lamina. FEZF1 (Fez family zinc finger protein 1), also known as Forebrain Embryonic Zinc Finger and Zinc finger protein 312B, is a 475 amino acid nuclear protein that is expressed in the olfactory epithelium and hypothalamus of mice. In FEZF1-deficient mice, axons of olfactory neurons do not reach the olfactory bulb, suggesting that FEXF1 is required for the penetration of olfactory axons though the basal lamina before innervation of the olfactory bulb. When FEZF1 translocates to the nucleus, it induces KRAS overexpression, resulting in activation of ERK-Signalling. Overexpression of FEZF1 leads to accelerated proliferation in cultured cells and increased tumour mass in mice. There are three isoforms of FEZF1 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11195R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11195R-A680
Lokale Artikelnummer::
BOSSBS-11195R-A680
Beschreibung:
BAF53b is a member of a family of actin-related proteins (ARPs), which shares significant sequence identity with conventional actins. Both actins and ARPs comprise an actin fold, which forms an ATP binding cleft. BAF53b is a component of the BAF (BRG/brm-associated factor) complex in mammals, which is functionally related to the SWI/SNF complex in S. cerevisiae and Drosophila, and is associated with chromatin remodeling to facilitate transcriptional activation. As neural progenitors exit the cell cycle, the highly homologous BAF53a subunit of the BAF complex is replaced by BAF53b. This subunit switch is essential for the transition from neural stem cells/progenitors to postmitotic neurons. BAF53b also plays a role in dendritic outgrowth, during which it is required to recruit the BAF complex and the dendritic regulator CREST to specific gene promoters. This function can not be performed by BAF53a.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9294R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9294R-A750
Lokale Artikelnummer::
BOSSBS-9294R-A750
Beschreibung:
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localises to cytoplasmic bodies and is essential for myogenic differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9332R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9332R-A680
Lokale Artikelnummer::
BOSSBS-9332R-A680
Beschreibung:
NHLRC2 (NHL repeat containing 2) is a 726 amino acid protein that contains six NHL repeats and one thioredoxin domain. Existing as two alternatively spliced isoforms, NHLRC2 is encoded by a gene that maps to human chromosome 10q25.3. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8519R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8519R-A680
Lokale Artikelnummer::
BOSSBS-8519R-A680
Beschreibung:
Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100% in various studies; as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30% of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9175R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9175R-A750
Lokale Artikelnummer::
BOSSBS-9175R-A750
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF10 (ring finger protein 10), also known as RIE2, is an 811 amino acid protein that localises to the cytoplasm and contains one RING-type zinc finger. Existing as multiple alternatively spliced isoforms, RNF10 interacts with MOX-2 and is thought to regulate its transcription in schwann cells, possibly playing a role in myelin formation. The gene encoding RNF10 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13161R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13161R-A750
Lokale Artikelnummer::
BOSSBS-13161R-A750
Beschreibung:
Fibulin-7 is a 439 amino acid extracellular matrix protein that belongs to the Fibulin family. Containing two EGF-like domains and one sushi (CCP/SCR) domain, Fibulin-7 exists as four alternatively spliced isoforms. Fibulin-7 is considered an adhesion protein that interacts with extracellular matrix molecules in developing teeth, and may be involved in differentiation and maintenance of odontoblasts as well as in dentin formation. Fibulin-7 is post-translationally glycosylated with N-linked oligosaccharides and interacts with heparin, fibronectin, fibulin-1 and DSP (dentin sialophosphoprotein). Fibulin-7 is encoded by a gene located on human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15236R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15236R-A488
Lokale Artikelnummer::
BOSSBS-15236R-A488
Beschreibung:
Making up nearly 6% of the human genome, chromosome 6 contains around 1200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf201 gene product has been provisionally designated C6orf201 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8453R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8453R-A750
Lokale Artikelnummer::
BOSSBS-8453R-A750
Beschreibung:
Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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