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COMBI-BLOCKS
Artikel-Nr:
(PRSI40-572)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-572
Lokale Artikelnummer::
PRSI40-572
Beschreibung:
Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor Beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human Beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (238 total amino acid residues). The three disulfide bonds are required for biological activity.Manufactured using all non-animal reagents.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-821)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-821
Lokale Artikelnummer::
PRSI91-821
Beschreibung:
CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7305P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7305P
Lokale Artikelnummer::
PRSI7305P
Beschreibung:
16 amino acids near the amino terminus of human TIAF.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-124)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-124
Lokale Artikelnummer::
PRSI90-124
Beschreibung:
DLL1 (Delta-like protein; Delta1) is essential for postnatal arteriogenesis and contributes to tumour progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-798)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-798
Lokale Artikelnummer::
PRSI91-798
Beschreibung:
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-444)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-444
Lokale Artikelnummer::
PRSI90-444
Beschreibung:
CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4289P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4289P
Lokale Artikelnummer::
PRSI4289P
Beschreibung:
KIF5 peptide is used for blocking the activity of KIF5 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6223P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6223P
Lokale Artikelnummer::
PRSI6223P
Beschreibung:
MYOZAP peptide is used for blocking the activity of MYOZAP antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-318)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-318
Lokale Artikelnummer::
PRSI90-318
Beschreibung:
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognises beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognises alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6407P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6407P
Lokale Artikelnummer::
PRSI6407P
Beschreibung:
SPRYD4 peptide is used for blocking the activity of SPRYD4 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-317)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-317
Lokale Artikelnummer::
PRSI91-317
Beschreibung:
FAM3C, also called interleukin-like EMT inducer, usually exist in most secretory epithelia. It belongs to the FAM3 family according to their sequence similarities. The up-regulation and/or mislocalization in breast cancer and liver carcinoma cells of FAM3C is strongly correlated with metastasis formation and survival. FAM3C can be involved in retinal laminar formation and promote epithelial to mesenchymal transition.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-068)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-068
Lokale Artikelnummer::
PRSI91-068
Beschreibung:
Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3391P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3391P
Lokale Artikelnummer::
PRSI3391P
Beschreibung:
TAB3 peptide is used for blocking the activity of TAB3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-558)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-558
Lokale Artikelnummer::
PRSI91-558
Beschreibung:
Gastric Triacylglycerol Lipase (LIPF) belongs to the AB hydrolase superfamily. LIPF is an important lipase during the digestion of dietary lipids in cystic fibrosis. LIPF is involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. LIPF is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. LIPF acts distinct roles in neutral lipid metabolism.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-563)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-563
Lokale Artikelnummer::
PRSI91-563
Beschreibung:
Protein O-Linked-Mannose beta -1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3623P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3623P
Lokale Artikelnummer::
PRSI3623P
Beschreibung:
CRMP1 peptide is used for blocking the activity of CRMP1 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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