Drucken
Sie suchten nach:
8 899 results were found
Proteine und Peptide
Artikel-Nr:
(PRSI6325P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6325P
Lokale Artikelnummer::
PRSI6325P
Beschreibung:
VASH1 peptide is used for blocking the activity of VASH1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-567)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-567
Lokale Artikelnummer::
PRSI92-567
Beschreibung:
Insulin-like growth factors (IGFs) comprise a family of endocrine, paracrine and autocrine polypeptides consisting of the ligands IGF1 and IGF2, two receptors (IGF1R, IGF2R), at least 6 IGF-binding proteins (IGFBPs) and IGFBP proteases. Among the binding proteins, IGFBP6 is unique because of its N-terminal disulphide linkages and its marked binding preference for IGF2. It is a potent inhibitor of the interaction between IGF2 and its receptor IGF1R, thus preventing major functions of IGF2, such as induction of proliferation, differentiation, cell adhesion, or colony formation. In particular, IGFBP-6 inhibited the growth of neuroblastoma and rhabdomyosarcoma xenografts. GFBP-6 is expressed in many tissues, including lung, liver, gut and the central nervous system.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3875P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3875P
Lokale Artikelnummer::
PRSI3875P
Beschreibung:
Bfl-1 peptide is used for blocking the activity of Bfl-1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-479)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-479
Lokale Artikelnummer::
PRSI90-479
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4639P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4639P
Lokale Artikelnummer::
PRSI4639P
Beschreibung:
Wnt10a peptide is used for blocking the activity of Wnt10a antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-335)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-335
Lokale Artikelnummer::
PRSI90-335
Beschreibung:
TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to five distinct receptors: TRAIL-R1 (DR4; Apo2;CD261; TNFRSF10A), TRAIL-R2 (DR5; KILLER; TRICK2A;TRICK2B; CD262; TNFRSF10B), TRAIL-R3 (DcR1;LIT; TRID; CD263; TNFRSF10C), TRAIL-R4 (DcR2;TRUNDD; CD264; TNFRSF10D), and osteoprotegerin (OPG; OCIF; TNFRSF11B). Trimerised TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducing the formation of the so-called multiprotein death-inducing signalling complex (DISC).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-129)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-129
Lokale Artikelnummer::
PRSI91-129
Beschreibung:
Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 R alpha and IL-20 R beta . The second is composed of IL-22 R and IL-20 R beta . Whereas the IL-22 R/IL-20 R beta complex is shared with IL-24, the IL-20 R alpha/IL-20 R beta complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF- alpha and MCP-1. Initial functional studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neonatal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-448)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-448
Lokale Artikelnummer::
PRSI91-448
Beschreibung:
Oncostatin-M-Specific Receptor Subunit beta (OSMR beta ) is a 150 - 180 kDa member of the IL-6 receptor family. OSMR beta associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMR beta associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMR beta cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2136P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2136P
Lokale Artikelnummer::
PRSI2136P
Beschreibung:
APP peptide is used for blocking the activity of APP antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4373P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4373P
Lokale Artikelnummer::
PRSI4373P
Beschreibung:
TOCA-1 peptide is used for blocking the activity of TOCA-1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3457P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3457P
Lokale Artikelnummer::
PRSI3457P
Beschreibung:
Caspase-5 peptide is used for blocking the activity of Caspase-5 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-050)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-050
Lokale Artikelnummer::
PRSI90-050
Beschreibung:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an adipokine that is localised to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
VE:
1 * 10 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
The globular subunit of adipocyte complement-related protein of 30 kDa (ACRP-30) is a naturally occurring cleavage product of adiponectin, a protein made exclusively by adipocytes. ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3). Human FLT-3 ligand is active on mouse cells.
Artikel-Nr:
(PRSI4425P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4425P
Lokale Artikelnummer::
PRSI4425P
Beschreibung:
ATG16 peptide is used for blocking the activity of ATG16 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
