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Proteine und Peptide
Artikel-Nr:
(PRSI90-231)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-231
Lokale Artikelnummer::
PRSI90-231
Beschreibung:
Tumour necrosis factor (TNF, cachexin or cachectin and formerly known as tumour necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. MultimericTNF-alpha™ is a high activity construct in which two trimeric TNF-alpha ligands are artificially linked via the collagen domain of ACRP30. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (TNF-alpha (human) (multimeric) (rec. ) (Prod. No. AG-40B-0019). Since the MultimericTNF-alpha™ mimics the membrane-bound form (forms oligomers higher than trimer), it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation, either "normal" TNF-alpha or MultimericTNF-alpha™ can be used.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI5135P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5135P
Lokale Artikelnummer::
PRSI5135P
Beschreibung:
FKBP15 peptide is used for blocking the activity of FKBP15 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-053)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-053
Lokale Artikelnummer::
PRSI91-053
Beschreibung:
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-720)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-720
Lokale Artikelnummer::
PRSI96-720
Beschreibung:
TIMP metallopeptidase inhibitor 1 is also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family.There are four members of the family, TIMP1,TIMP2,TIMP3 and TIMP4. TIMP1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-075)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-075
Lokale Artikelnummer::
PRSI92-075
Beschreibung:
Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-769)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-769
Lokale Artikelnummer::
PRSI91-769
Beschreibung:
Proenkephalin-A is a secreted protein that belongs to the opioid neuropeptide precursor family. Proenkephalin-A is an endogenous opioid polypeptide hormone which, via proteolyic cleavage, produces the enkephalin peptides [Met]enkephalin, and to a lesser extent, [Leu]enkephalin. Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Proenkephalin-A (114-133) and Proenkephalin-A (237-258) increase glutamate release in the striatum. Proenkephalin-A (114-133) decreases GABA concentration in the striatum.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5475P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5475P
Lokale Artikelnummer::
PRSI5475P
Beschreibung:
SRPX2 peptide is used for blocking the activity of SRPX2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-133)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-133
Lokale Artikelnummer::
PRSI90-133
Beschreibung:
Granulins have possible cytokine-like activity. They are important in normal development, inflammation, wound repair, and tumorigenesis.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI1131P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1131P
Lokale Artikelnummer::
PRSI1131P
Beschreibung:
TACE peptide is used for blocking the activity of TACE antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3193P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3193P
Lokale Artikelnummer::
PRSI3193P
Beschreibung:
CARMA3 peptide is used for blocking the activity of CARMA3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5065P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5065P
Lokale Artikelnummer::
PRSI5065P
Beschreibung:
LRFN1 peptide is used for blocking the activity of LRFN1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3125P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3125P
Lokale Artikelnummer::
PRSI3125P
Beschreibung:
IRAK4 peptide is used for blocking the activity of IRAK-4 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6181P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6181P
Lokale Artikelnummer::
PRSI6181P
Beschreibung:
SLAMF9 peptide is used for blocking the activity of SLAMF9 antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.
Artikel-Nr:
(PRSI6883P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6883P
Lokale Artikelnummer::
PRSI6883P
Beschreibung:
TTYH1 peptide is used for blocking the activity of TTYH1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-434)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-434
Lokale Artikelnummer::
PRSI90-434
Beschreibung:
Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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