Drucken
Sie suchten nach:
8 899 results were found
Proteine und Peptide
Artikel-Nr:
(PRSI6951P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6951P
Lokale Artikelnummer::
PRSI6951P
Beschreibung:
TCTEX1D1 peptide is used for blocking the activity of TCTEX1D1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-587)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-587
Lokale Artikelnummer::
PRSI91-587
Beschreibung:
Mouse Interleukin-36 alpha(Il-36a)is a member of the IL-1 family.IL¬1 alpha,IL¬1 beta and IL-18 are potent inflammatory cytokines whose activities are dependent on heterodimeric receptors of the IL-1R superfamily, and which are regulated by soluble antagonists. Il36a is expressed in many cells, including monocytes, B cells, and T cells, immune system and fetal brains. Il36a is a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. It is a part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. It seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. It Induces the production of proinflammatory cytokines, including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23 in bone marrow-derived dendritic cells (BMDCs). Moreover, it is involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II and can induce the production of IFN-gamma, IL-4 and IL-17 by cultured CD4+ T cells and splenocytes. Il36a may play a role in proinflammatory effects in the lung: induces the expression of CXCL1 and CXCL2 in the lung, and the expression of TNF-alpha, IL-36c, IL-1A, IL-1B, CXCL1 and CXCL2 in isolated splenic CD11c+ alveolar macrophages. It may be involved in T cell maturation by stimulating the surface expression of CD40 and modestly CD80 and CD86 in splenic CD11c+ cells and CD4+ T cell proliferation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-332)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-332
Lokale Artikelnummer::
PRSI90-332
Beschreibung:
DLL3 (Delta-like protein 3; Delta3) inhibits primary neurogenesis. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 binds and activates Notch-1 or another Notch receptor. Defects in DLL3 are the cause of spondylocostal dysostosis type 1 (SCDO1).
VE:
1 * 10 µG
Artikel-Nr:
(PRSI4077P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4077P
Lokale Artikelnummer::
PRSI4077P
Beschreibung:
MAPKAP1 peptide is used for blocking the activity of MAPKAP1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3759P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3759P
Lokale Artikelnummer::
PRSI3759P
Beschreibung:
DDX3 peptide is used for blocking the activity of DDX3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-886)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-886
Lokale Artikelnummer::
PRSI91-886
Beschreibung:
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases involved in the development of embryonic nervous and vascular systems. EPHB1 contains two fibronectin type-III domains, one protein kinase domain and one Sterile Alpha Motif (SAM)domain. EPHB1 is able to stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which is also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to Ephrin-B1, Ephrin-B2 and Ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXW-RP3065)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-RP3065
Lokale Artikelnummer::
PRSIXW-RP3065
Beschreibung:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5169P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5169P
Lokale Artikelnummer::
PRSI5169P
Beschreibung:
ST3gal6 peptide is used for blocking the activity of ST3gal6 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-362)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-362
Lokale Artikelnummer::
PRSI91-362
Beschreibung:
Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM). Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM; Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site, plus cleavage sites for elastase, thrombin, and plasmin.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-006)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-006
Lokale Artikelnummer::
PRSI90-006
Beschreibung:
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7343P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7343P
Lokale Artikelnummer::
PRSI7343P
Beschreibung:
18 amino acids peptide near the amino terminus of human DIS3.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-095)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-095
Lokale Artikelnummer::
PRSI96-095
Beschreibung:
Cluster of Differentiation 31 (CD31) is also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils, certain tumors, and is the only known member of the CAM family on platelets. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. CD31 plays a key role in removing aged neutrophils from the body. CD31 mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. In addition, it has been shown that CD31 expression is up-regulated by LPS stimulation, and might function as a feedback negative regulator of LPS inflammatory response in macrophages.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI91-574)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-574
Lokale Artikelnummer::
PRSI91-574
Beschreibung:
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-554)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-554
Lokale Artikelnummer::
PRSI91-554
Beschreibung:
Vitelline membrane outer layer protein 1 homolog (VMO1) belongs to the VMO1 family is a 202 amino acid secreted protein. Exact function not known, component of the outer membrane of the vitelline layer of the egg. Seems to be able to synthesize N-acetylchito-oligosaccharides (n=14-15) from hexasaccharides of N-acetylglucosamine in a manner similar to the transferase activity of lysozyme.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-669)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-669
Lokale Artikelnummer::
PRSI91-669
Beschreibung:
Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF2 is a secreted protein and specifically expressed in the stomach. TFF2 inhibits gastrointestinal motility and gastric acid secretion. TFF2 could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-940)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-940
Lokale Artikelnummer::
PRSI91-940
Beschreibung:
V-set and immunoglobulin domain-containing protein 4(VSIG4) is a transmembrane protein contains a signal peptide, a V-type Ig-like domain, a C2-type Ig-like domain, several potential O-glycosylation sites, and an intracellular domain with 2 potential phosphorylation sites and is structurally related to the B7 family of immune regulatory proteins. This protein is also a receptor for the complement component 3 fragments C3b and iC3b.The main function is strong negative regulator of T-cell proliferation and IL2 production and it is also potent inhibitor of the alternative complement pathway convertases. It abundantly expressed in several fetal tissues such as adult tissues, highest expression in lung and placenta and it also expressed in resting macrophages.
VE:
1 * 50 µG
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
