1-Bromo-4-(2,2-difluorocyclopropyl)benzene
Artikel-Nr:
(BOSSBS-11797R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11797R-CY3
Lokale Artikelnummer::
BOSSBS-11797R-CY3
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH3A2 (aldehyde dehydrogenase 3 family, member A2), also known as SLS, FALDH or ALDH10, is a 485 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the endoplasmic reticulum and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH3A2 catalyzes the NAD+-dependent oxidation of long-chain aliphatic aldehydes to fatty acids, a process that is necessary for detoxification and lipid metabolism. Defects in the gene encoding ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS), an autosomal recessive neurocutaneous disorder characterized by severe mental retardation, seizures and speech defects. Multiple isoforms of ALDH3A2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7638R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7638R-CY7
Lokale Artikelnummer::
BOSSBS-7638R-CY7
Beschreibung:
Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
VE:
1 * 100 µl
Artikel-Nr:
(87710.180)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC87710.180
Beschreibung:
Kaliumtetraiodomercurat(II)-Reagenz, Lösung B (Natronlauge 20%) Reag. Ph. Eur. 1071600 für die Bestimmung von Ammoniak und Ammoniumsalzen
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-10255R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10255R-A555
Lokale Artikelnummer::
BOSSBS-10255R-A555
Beschreibung:
The amino acid Citrulline is required to detoxify the liver from ammonia, which is a waste product of the body from oxidation. Citrulline promotes energy and assists with the immune system. This unusual amino acid is formed in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. It is then combined with aspartic acid to form arginosuccinic acid, which later is metabolized into the amino acid arginine.
VE:
1 * 100 µl
Artikel-Nr:
(USBIA1334-33H)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A1334-33H
Lokale Artikelnummer::
USBIA1334-33H
Beschreibung:
Anti-ALDH1A1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-10255R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10255R-A488
Lokale Artikelnummer::
BOSSBS-10255R-A488
Beschreibung:
The amino acid Citrulline is required to detoxify the liver from ammonia, which is a waste product of the body from oxidation. Citrulline promotes energy and assists with the immune system. This unusual amino acid is formed in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. It is then combined with aspartic acid to form arginosuccinic acid, which later is metabolized into the amino acid arginine.
VE:
1 * 100 µl
Lieferant:
VWR Chemicals
Beschreibung:
Devarda's alloy is used as reducing agent in analytical chemistry for the determination of nitrates after their reduction to ammonia under alkaline.
Artikel-Nr:
(BOSSBS-11797R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11797R-A750
Lokale Artikelnummer::
BOSSBS-11797R-A750
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH3A2 (aldehyde dehydrogenase 3 family, member A2), also known as SLS, FALDH or ALDH10, is a 485 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the endoplasmic reticulum and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH3A2 catalyses the NAD+-dependent oxidation of long-chain aliphatic aldehydes to fatty acids, a process that is necessary for detoxification and lipid metabolism. Defects in the gene encoding ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS), an autosomal recessive neurocutaneous disorder characterised by severe mental retardation, seizures and speech defects. Multiple isoforms of ALDH3A2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12460R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12460R-HRP
Lokale Artikelnummer::
BOSSBS-12460R-HRP
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-CY7
Lokale Artikelnummer::
BOSSBS-11726R-CY7
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-A555
Lokale Artikelnummer::
BOSSBS-11726R-A555
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-A647
Lokale Artikelnummer::
BOSSBS-11726R-A647
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1961R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1961R-A750
Lokale Artikelnummer::
BOSSBS-1961R-A750
Beschreibung:
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBSM-1621M-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BSM-1621M-A750
Lokale Artikelnummer::
BOSSBSM-1621M-A750
Beschreibung:
Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7638R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7638R-HRP
Lokale Artikelnummer::
BOSSBS-7638R-HRP
Beschreibung:
Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1961R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1961R-CY5
Lokale Artikelnummer::
BOSSBS-1961R-CY5
Beschreibung:
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
VE:
1 * 100 µl
Preis auf Anfrage
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