6-Chloropyrido[3,4-d]pyrimidin-4(3H)-one
Artikel-Nr:
(BOSSBS-7756R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7756R
Lokale Artikelnummer::
BOSSBS-7756R
Beschreibung:
MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5844R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5844R
Lokale Artikelnummer::
BOSSBS-5844R
Beschreibung:
May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6091R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6091R-A680
Lokale Artikelnummer::
BOSSBS-6091R-A680
Beschreibung:
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation.
VE:
1 * 100 µl
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Acriflavine also interacts with HIF-1α (hypoxia-inducible factor 1 α) and HIF-2α, and thereby suppresses dimer formation of HIF-1 and transcriptional function. It also has negative effect on tumor growth and vascularization. Acriflavine also exhibits trypanocidal, antibacterial and antiviral activities.
Artikel-Nr:
(BOSSBS-5790R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5790R-FITC
Lokale Artikelnummer::
BOSSBS-5790R-FITC
Beschreibung:
May modulate the formation of a collagenous extracellular matrix.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6091R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6091R-A488
Lokale Artikelnummer::
BOSSBS-6091R-A488
Beschreibung:
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation
VE:
1 * 100 µl
Artikel-Nr:
(8.42196.0025)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.42196.0025
Lokale Artikelnummer::
MERC8.42196.0025
Beschreibung:
1-Ethyl-2-pyrrolidon zur Synthese, Sigma-Aldrich®
VE:
1 * 25 mL
Artikel-Nr:
(BOSSBS-5790R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5790R-HRP
Lokale Artikelnummer::
BOSSBS-5790R-HRP
Beschreibung:
May modulate the formation of a collagenous extracellular matrix.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9301R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9301R-A680
Lokale Artikelnummer::
BOSSBS-9301R-A680
Beschreibung:
SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localised asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle; it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9301R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9301R-A750
Lokale Artikelnummer::
BOSSBS-9301R-A750
Beschreibung:
SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localised asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle; it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9301R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9301R-A488
Lokale Artikelnummer::
BOSSBS-9301R-A488
Beschreibung:
SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle; it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1495R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1495R-A350
Lokale Artikelnummer::
BOSSBS-1495R-A350
Beschreibung:
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1495R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1495R-FITC
Lokale Artikelnummer::
BOSSBS-1495R-FITC
Beschreibung:
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7756R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7756R-FITC
Lokale Artikelnummer::
BOSSBS-7756R-FITC
Beschreibung:
MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7756R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7756R-A647
Lokale Artikelnummer::
BOSSBS-7756R-A647
Beschreibung:
MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(8.20597.0100)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.20597.0100
Lokale Artikelnummer::
MERC8.20597.0100
Beschreibung:
Ethyl-3,4,5-trihydroxybenzoat zur Synthese, Sigma-Aldrich®
VE:
1 * 100 g
Preis auf Anfrage
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