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(+\/-)-3-(trans-2-(Trifluoromethyl)cyclopropyl)benzoic+acid
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(+\/-)-3-(trans-2-(Trifluoromethyl)cyclopropyl)benzoic+acid
Artikel-Nr:
(BOSSBS-4281R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4281R-A750
Lokale Artikelnummer::
BOSSBS-4281R-A750
Beschreibung:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilises p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilisation and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilising the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC7833-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC7833-1G
Lokale Artikelnummer::
APOSPC7833-1G
Beschreibung:
5-Chlor-2-fluorbenzotrifluorid 98%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bis(trifluoromethanesulphonyl)methane 97%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Brom-4-chlorbenzotrifluorid 97%
Lieferant:
Thermo Scientific
Beschreibung:
α,α,α,α',α',α'-Hexafluor-3,5-xylidin 98+%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Mefloquine hydrochloride
Artikel-Nr:
(ACRO466010010)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
466010010
Lokale Artikelnummer::
ACRO466010010
Beschreibung:
Cinacalcet hydrochloride
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD33677-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD33677-5G
Lokale Artikelnummer::
BLDPBD33677-5G
Beschreibung:
α,α,α-Trifluor-o-toluonitril 98%
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-4281R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4281R-A680
Lokale Artikelnummer::
BOSSBS-4281R-A680
Beschreibung:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilises p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilisation and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilising the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4281R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4281R-A555
Lokale Artikelnummer::
BOSSBS-4281R-A555
Beschreibung:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
Dimethylcyclohexan-1,4-dicarboxylat (Gemisch der cis- und trans-Isomeren)
Lieferant:
Alfa Aesar
Beschreibung:
2-Chlor-5-(trifluormethyl)anilin ≥97%
Lieferant:
Honeywell Chemicals
Beschreibung:
Decahydronaphthalin (Gemisch der cis- und trans-Isomeren) 98%, Reagenzqualität
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-Fluor-2-(trifluormethylsulfonyl)benzol
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Chlor-6-fluorbenzotrifluorid 98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Bromo-3-methylbenzotrifluoride 95%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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