2,5-Dibromphenol
Artikel-Nr:
(BOSSBS-11363R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11363R-HRP
Lokale Artikelnummer::
BOSSBS-11363R-HRP
Beschreibung:
SNAP 29 is a 258 amino acid protein that localizes to the membrane and the cytoplasm, as well as to the cell junction, and contains one t-SNARE coiled-coil homology domain. Expressed in liver, heart, brain, kidney, placenta, lung, spleen, pancreas and skeletal muscle, SNAP 29 binds tightly to Syntaxins and, via this binding, is involved in membrane trafficking events. Defects in the gene encoding SNAP 29 are the cause of CEDNIK syndrome, a neurocutaneous syndrome that is associated with cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. The gene encoding SNAP 29 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6606R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6606R-HRP
Lokale Artikelnummer::
BOSSBS-6606R-HRP
Beschreibung:
There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9115R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9115R-FITC
Lokale Artikelnummer::
BOSSBS-9115R-FITC
Beschreibung:
Unknown. Candidate gene encoding tumor antigens.Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6606R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6606R-A750
Lokale Artikelnummer::
BOSSBS-6606R-A750
Beschreibung:
There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Methyl-3,5-di-tert-butyl-4-hydroxybenzoate 98%
Lieferant:
VWR Collection
Beschreibung:
Moderne Mikroskope für Durchlicht-Routineanwendungen in Laboren. Auch ideal für Unterricht und Ausbildung, insbesondere im medizinischen Bereich.
Artikel-Nr:
(SIALD205206-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D205206-10G
Lokale Artikelnummer::
SIALD205206-10G
Beschreibung:
N,N'-Diphenylbenzidin, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(1012032.)
Lieferant:
USP
Hersteller-Artikelnummer::
1012032
Lokale Artikelnummer::
USPH1012032
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 20 mg
Artikel-Nr:
(SIAL803421-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
803421-50MG
Lokale Artikelnummer::
SIAL803421-50MG
Beschreibung:
Succinimidyl-diazirine (SDA) reagents are a new class of crosslinkers that combine proven amine-reactive chemistry with an innovative and efficient diazirine-based photochemistry for conjugating amine-containing molecules to nearly any other functional group. The SDA crosslinkers include six compounds differing in spacer arm lengths, ability to cleave the crosslinked proteins, and presence or absence of a charged group for membrane permeability. Protein crosslinking is an important technique used to understand protein structure and to stabilize protein-protein interactions, and these SDA reagents extend the efficiency and range of interactions that can be explored by this approach.
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-8548R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8548R-A647
Lokale Artikelnummer::
BOSSBS-8548R-A647
Beschreibung:
The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8548R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8548R-A750
Lokale Artikelnummer::
BOSSBS-8548R-A750
Beschreibung:
The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Dimethyl-trans-cyclohexan-1,4-dicarboxylat 99+%
Artikel-Nr:
(80011-1)
Lieferant:
Biotium
Hersteller-Artikelnummer::
80011-1
Lokale Artikelnummer::
BTIU80011-1
Beschreibung:
Calcein AM is a widely used green fluorescent cell marker. Calcein AM is membrane-permeant and thus can be introduced into cells via incubation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9261R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9261R-HRP
Lokale Artikelnummer::
BOSSBS-9261R-HRP
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF185 (ring finger protein 185), also known as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative splicing, and the gene encoding RNF185 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9261R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9261R-A488
Lokale Artikelnummer::
BOSSBS-9261R-A488
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF185 (ring finger protein 185), also known as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative splicing, and the gene encoding RNF185 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
VE:
1 * 100 µl
Preis auf Anfrage
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