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(3,4-Dimethoxyphenyl)essigsäurehydrazid
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(3,4-Dimethoxyphenyl)essigsäurehydrazid
Artikel-Nr:
(BOSSBS-11695R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11695R-CY7
Lokale Artikelnummer::
BOSSBS-11695R-CY7
Beschreibung:
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Artikel-Nr:
(EHERL12453400ME)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L12453400ME
Lokale Artikelnummer::
EHERL12453400ME
Beschreibung:
Organic Standard, 3,4-Dichlorphenol 10 µg/ml in Methanol, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(SIAL11229-2.5L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
11229-2.5L
Lokale Artikelnummer::
SIAL11229-2.5L
Beschreibung:
Ammoniumsulfit 34% in wässriger Lösung, Sigma-Aldrich®
VE:
1 * 2,5 L
Lieferant:
Biotium
Beschreibung:
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
Lieferant:
Biotium
Beschreibung:
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
Artikel-Nr:
(BOSSBS-11287R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11287R-A647
Lokale Artikelnummer::
BOSSBS-11287R-A647
Beschreibung:
Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1). Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4). In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2). Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1). The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5). The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5372R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5372R-FITC
Lokale Artikelnummer::
BOSSBS-5372R-FITC
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5373R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R-CY7
Lokale Artikelnummer::
BOSSBS-5373R-CY7
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5373R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R-HRP
Lokale Artikelnummer::
BOSSBS-5373R-HRP
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(A6882.0100)
Lieferant:
PanReac AppliChem
Hersteller-Artikelnummer::
A6882.0100
Lokale Artikelnummer::
APLIA6882.0100
Beschreibung:
D(+)-Raffinose Pentahydrat
VE:
1 * 100 g
Lieferant:
Cayman Chemical
Beschreibung:
Calcein-AM ist ein zelldurchdringender Farbstoff, der nach dem Transport in lebende Zellen durch intrazelluläre Esterasen abgespalten und in Calcein umgewandelt wird, das die Membran nicht durchdringen kann.
Artikel-Nr:
(PRSI24-414)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-414
Lokale Artikelnummer::
PRSI24-414
Beschreibung:
Anti-V alpha TCR Recombinant Antibody [Clone: 34]
VE:
1 * 0,2 mg
Artikel-Nr:
(SIAL440736-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
440736-1G
Lokale Artikelnummer::
SIAL440736-1G
Beschreibung:
4-Thioxo-3,4-dihydro-2(1H)-pyrimidinon, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(BLEG577609)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
577609
Lokale Artikelnummer::
BLEG577609
Beschreibung:
Mouse recombinant IL-34 (from CHO cells)
VE:
1 * 1 Pack.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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