(4-Isopropylphenoxy)acetyl+chloride
Artikel-Nr:
(BOSSBS-0518R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0518R-CY3
Lokale Artikelnummer::
BOSSBS-0518R-CY3
Beschreibung:
Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.
VE:
1 * 100 µl
Artikel-Nr:
(ENAMEN300102440.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN300102440.1G
Lokale Artikelnummer::
ENAMEN300102440.1G
Beschreibung:
4-Acetyl-2-chlorpyridin
VE:
1 * 1 g
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Artikel-Nr:
(8.14656.9045)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.14656.9045
Lokale Artikelnummer::
MERC8.14656.9045
Beschreibung:
Antimon(III)chlorid ≥99,0% (durch Iodometrie) zur Synthese, Sigma-Aldrich®
VE:
1 * 45 kg
Artikel-Nr:
(BOSSBS-11018R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11018R
Lokale Artikelnummer::
BOSSBS-11018R
Beschreibung:
This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
VE:
1 * 100 µl
Artikel-Nr:
(1.12219.0250)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.12219.0250
Lokale Artikelnummer::
MERC1.12219.0250
Beschreibung:
Lanthan(III)chlorid Heptahydrat analytisches Reagens, Supelco®
VE:
1 * 250 g
Artikel-Nr:
(8.04079.0025)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.04079.0025
Lokale Artikelnummer::
MERC8.04079.0025
Beschreibung:
Germanium(IV)chlorid zur Synthese, Sigma-Aldrich®
VE:
1 * 25 mL
Lieferant:
Sigma-Aldrich
Beschreibung:
N-Acetyl-L-cystein, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-7618R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7618R-A680
Lokale Artikelnummer::
BOSSBS-7618R-A680
Beschreibung:
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
N-Acetyl-L-methionin, Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
2-Acetyl-5-chlorthiophen
Lieferant:
Sigma-Aldrich
Beschreibung:
9-Fluorenylmethylchlorformiat (Fmoc-Chlorid), Supelco®
Artikel-Nr:
(1.05512.0250)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.05512.0250
Lokale Artikelnummer::
MERC1.05512.0250
Beschreibung:
Eisen(III)chlorid (10% Fe) in wässriger Lösung, EMSURE® zur Analyse, Supelco®
VE:
1 * 250 mL
Lieferant:
MP Biomedicals
Beschreibung:
N-Acetyl-β-D-mannosamine hydrate is used as a substrate to identify, differentiate and characterise enzymes such as N-acetyl-glucosamine epimerase(s) and aldolase(s). N-Acetyl-D-mannosamine is used for the synthesis of of N-acetylneuraminic acid.
Artikel-Nr:
(BOSSBS-0518R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0518R-CY7
Lokale Artikelnummer::
BOSSBS-0518R-CY7
Beschreibung:
Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7618R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7618R-A350
Lokale Artikelnummer::
BOSSBS-7618R-A350
Beschreibung:
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Nickel(II)chlorid Hexahydrat, EMSURE® zur Analyse, Supelco®
Preis auf Anfrage
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