β-tri-Calciumphosphat+(β-Phase)
Lieferant:
GESTIGKEIT HARRY
Beschreibung:
Glass ceramic heating plate, which is extremely resistant to breakage and changes of temperature, will not distort, is permeable to ultra-violet light and also highly acid-resistant.
Artikel-Nr:
(GILI21063024)
Lieferant:
GILSON LCMS
Hersteller-Artikelnummer::
21063024
Lokale Artikelnummer::
GILI21063024
Beschreibung:
TRILUTION® LH provides a solution for customers using Windows 10 and is a comprehensive software package for seamless automation of all liquid handling and solid phase extraction (SPE) methods. With its intuitive interface, simple drag-and-drop method creation, and application simulation, it combines flexibility and ease of use.
VE:
1 * 1 ST
Lieferant:
MACHEREY-NAGEL
Beschreibung:
CHROMABOND® Na₂SO₄/Florisil® is a combination phase for SPE of hydrocarbons from water.
Lieferant:
Resonac
Beschreibung:
C18M are monometric type ODS columns, fully endcapped high purity silica (99,99% or higher). Ideal for reversed phase separation.
Lieferant:
MACHEREY-NAGEL
Beschreibung:
CHROMABOND® C4 is a butyl modified silica phase for SPE.
Lieferant:
Avantor Fluid Handling
Beschreibung:
Mit Dreiphasenmotoren zur Schaffung eines Systems mit variabler Geschwindigkeit verwendbar.
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Lieferant:
HAMILTON BONADUZ
Beschreibung:
100 Å-Säulen auf Kieselgelbasis für Umkehrphasenchromatographie.
Lieferant:
Restek
Beschreibung:
Rtx-200-Säulen haben viele anspruchsvolle Trennungen durchgeführt. Die stationäre Trifluorpropylmethylpolysiloxan-Phase verfügt über eine einzigartige Selektivität, die die Elutionsreihenfolge ändert und Verbindungen auflöst, die Phenyl-, Cyano- oder Carbowax-Phasen nicht auflösen können. Diese Säulen bieten außergewöhnliche thermische Stabilität, geringes Bluten und hervorragende Inertheit – selbst für aktive Verbindungen wie Phenole und mit empfindlichen Detektoren wie ECDs, NPDs und MSDs.
Artikel-Nr:
(7511-04)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR7511-04
Beschreibung:
Diese Festphasenextraktionssäule ist für die Extraktion von PCBs in Öl (verschmutzte Proben) in Kombination mit SPE-Kieselgel konzipiert.
VE:
1 * 50 ST
Lieferant:
VARIAN
Beschreibung:
Säulentyp: HPLC-Säule, PLRP-S, Seperation of synthetic peptides & recombinant peptides and proteins by reverse phase, Ø int.: 100,00 mm, Länge: 300 mm, Porengröße: 300 Å, Partikelgröße: 8 µm
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Artikel-Nr:
(BNUM0680-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0680-50
Lokale Artikelnummer::
BTIUBNUM0680-50
Beschreibung:
This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-11321R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11321R-A680
Lokale Artikelnummer::
BOSSBS-11321R-A680
Beschreibung:
Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2. Islet-2 is a nuclear protein that contains two N-terminal LIM domains, followed by a homeodomain and a serine/glutamine/threonine-rich C-terminus. Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways. Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates. Somatic, but not visceral, motor neurons maintain Islet-2 expression at later embryonic stages. An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character. Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9367R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9367R-A750
Lokale Artikelnummer::
BOSSBS-9367R-A750
Beschreibung:
In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation <i>in vivo</i>.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2527R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2527R-HRP
Lokale Artikelnummer::
BOSSBS-2527R-HRP
Beschreibung:
Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2527R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2527R-CY7
Lokale Artikelnummer::
BOSSBS-2527R-CY7
Beschreibung:
Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
VE:
1 * 100 µl
Preis auf Anfrage
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