3-[4-(3-Fluoropropoxy)phenyl]acrylic+acid
Artikel-Nr:
(SIAL483192-5ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
483192-5ML
Lokale Artikelnummer::
SIAL483192-5ML
Beschreibung:
1,4-Bis(dimethylsilyl)benzol, Sigma-Aldrich®
VE:
1 * 5 mL
Artikel-Nr:
(BOSSBS-13209R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13209R-A350
Lokale Artikelnummer::
BOSSBS-13209R-A350
Beschreibung:
FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0644R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R-A555
Lokale Artikelnummer::
BOSSBS-0644R-A555
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11879R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11879R-A750
Lokale Artikelnummer::
BOSSBS-11879R-A750
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
VE:
1 * 100 µl
Artikel-Nr:
(USBI036122)
Lieferant:
US Biological
Hersteller-Artikelnummer::
036122
Lokale Artikelnummer::
USBI036122
Beschreibung:
Anti-GNA11 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-3029R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3029R-CY5
Lokale Artikelnummer::
BOSSBS-3029R-CY5
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5436R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5436R-A750
Lokale Artikelnummer::
BOSSBS-5436R-A750
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8170R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8170R-CY3
Lokale Artikelnummer::
BOSSBS-8170R-CY3
Beschreibung:
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12475R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12475R-A350
Lokale Artikelnummer::
BOSSBS-12475R-A350
Beschreibung:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9025R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9025R-CY5.5
Lokale Artikelnummer::
BOSSBS-9025R-CY5.5
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3007R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3007R
Lokale Artikelnummer::
BOSSBS-3007R
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
VE:
1 * 100 µl
Lieferant:
CHROMACOL
Beschreibung:
Chromacol™, Chromatographieampullen-Verschlüsse, PE, Ø: 11 mm, PE Schnappverschluss, blau, 11 mm, mit Septum PTFE, mit 6-mm-Loch, Typ: 11-PSN(B)-T02
Artikel-Nr:
(SIAL683140-2G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
683140-2G
Lokale Artikelnummer::
SIAL683140-2G
Beschreibung:
Bis(1,5-cyclooctadien)rhodium(I)tetrafluoroborat Hydrat, Sigma-Aldrich®
VE:
1 * 2 g
Artikel-Nr:
(SIAL547816-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
547816-1G
Lokale Artikelnummer::
SIAL547816-1G
Beschreibung:
Tris[N,N-bis(trimethylsilyl)amid]europium(III), Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
Sigma-Aldrich
Beschreibung:
1,4-Bis(diphenylphosphino)butan, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
1,5-Bis(diphenylphosphino)pentan, Sigma-Aldrich®
Preis auf Anfrage
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