1,1-Diphenylhydrazin+Hydrochlorid
Lieferant:
Agilent
Beschreibung:
CrossLab, General purpose septa, Ø: 11 mm
Artikel-Nr:
(PROOMM0086.17)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0086.17
Lokale Artikelnummer::
PROOMM0086.17
Beschreibung:
Organic Standard, [5-[(Dimethylamino)methyl]furan-2-yl]methanol hydrochloride
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-8244R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8244R
Lokale Artikelnummer::
BOSSBS-8244R
Beschreibung:
Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XI, also referred to as carbonic anhydrase-related protein 11 precursor (CA-RP XI) or carbonic anhydrase-related protein 2 (CA-RP II), is a member of the carbonic anhydrase family that lacks two of the three Zn-binding motifs essential for carbonic anhydrase activity. For this reason, CA XI does not exhibit catalytic activity. It is expressed primarily in brain but is also found in spinal cord and thyroid. CA XI may play a role in brain development.Tissue specificity:Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid.
VE:
1 * 100 µl
Artikel-Nr:
(USBIC1385-25H)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C1385-25H
Lokale Artikelnummer::
USBIC1385-25H
Beschreibung:
Anti-CARD11 Goat polyclonal antibody
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.
Artikel-Nr:
(PROOBP835)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
BP835
Lokale Artikelnummer::
PROOBP835
Beschreibung:
Organic Standard, Venlafaxine hydrochloride assay standard
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-8562R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8562R-CY5.5
Lokale Artikelnummer::
BOSSBS-8562R-CY5.5
Beschreibung:
The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10% of patients with acute lymphoblastic leukemia (ALL) and 5% of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. MLLT11, also known as mixed-lineage leukemia translocated to 11 or AF1q, is a 90 amino acid MLL fusion partner. Based on the expression patterns of MLLT11, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML). Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Finally, MLLT11 has been shown to be differentially expressed in highly metastatic cells, in comparison with non-metastatic parent cells. Such findings suggest a role of MLLT11 in tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11399R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11399R
Lokale Artikelnummer::
BOSSBS-11399R
Beschreibung:
Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson’s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson’s disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8562R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8562R
Lokale Artikelnummer::
BOSSBS-8562R
Beschreibung:
The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10% of patients with acute lymphoblastic leukemia (ALL) and 5% of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. MLLT11, also known as mixed-lineage leukemia translocated to 11 or AF1q, is a 90 amino acid MLL fusion partner. Based on the expression patterns of MLLT11, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML). Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Finally, MLLT11 has been shown to be differentially expressed in highly metastatic cells, in comparison with non-metastatic parent cells. Such findings suggest a role of MLLT11 in tumorigenesis.
VE:
1 * 100 µl
Lieferant:
Thermo Fisher Scientific
Beschreibung:
0,8 ml, PE, Klar, Verschlussgröße: 11 mm, Septum: Blue PE septum, 11 mm
Artikel-Nr:
(1.03067.0025)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.03067.0025
Lokale Artikelnummer::
MERC1.03067.0025
Beschreibung:
N,N-Dimethyl-1,4-phenylendiammoniumdichlorid analytisches Reagens, Supelco®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-13209R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13209R-HRP
Lokale Artikelnummer::
BOSSBS-13209R-HRP
Beschreibung:
FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0644R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R-A350
Lokale Artikelnummer::
BOSSBS-0644R-A350
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins.
Artikel-Nr:
(BOSSBS-9025R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9025R-CY5
Lokale Artikelnummer::
BOSSBS-9025R-CY5
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
VE:
1 * 100 µl
Preis auf Anfrage
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