1,4-Bis(methoxydimethylsilyl)benzene
Artikel-Nr:
(BSENS-025-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-025-100
Lokale Artikelnummer::
BSENS-025-100
Beschreibung:
CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. FUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Nervous system. PHARMACEUTICAL: CNTF is being tested under the name Axokine by Regeneron Pharmaceuticals for treatment of human motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). As it induces substantial weight loss, preferentially of fat as opposed to lean body mass, it is being used for obesity treatment. SIMILARITY: Belongs to the CNTF family.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Bis(benzonitril)dichlorpalladium(II), Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
3,5-Bis(trifluormethyl)phenol
Artikel-Nr:
(444-1383)
Lieferant:
VWR Collection
Lokale Artikelnummer::
VWRI444-1383
Beschreibung:
Aufnahmeteller, groß, für Kolben bis 50 ml, Ø 62 mm
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Dithiodiglycol (Bis(2-hydroxyethyl)disulfid), Sigma-Aldrich®
Artikel-Nr:
(SIAL536539-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
536539-1G
Lokale Artikelnummer::
SIAL536539-1G
Beschreibung:
2,5-Bis(brommethyl)-4-(2-ethylhexyloxy)anisol, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(APOSOR317141-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR317141-1G
Lokale Artikelnummer::
APOSOR317141-1G
Beschreibung:
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid methyl ester
VE:
1 * 1 g
Artikel-Nr:
(MOLE28001437-5G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
28001437-5G
Lokale Artikelnummer::
MOLE28001437-5G
Beschreibung:
1,3-Bis(diphenylphosphino)propan
VE:
1 * 5 g
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Artikel-Nr:
(SIAL482617-500MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
482617-500MG
Lokale Artikelnummer::
SIAL482617-500MG
Beschreibung:
(R)-(-)-6,6'-Dibrom-1,1'-bi-2-naphthol, Sigma-Aldrich®
VE:
1 * 500 mg
Artikel-Nr:
(COBBPN-6038-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
PN-6038-1G
Lokale Artikelnummer::
COBBPN-6038-1G
Beschreibung:
2-(Bis-Boc-amino)-5-pyrimidinboronsäurepinakolester
VE:
1 * 1 g
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Artikel-Nr:
(BOSSBS-11678R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11678R-CY7
Lokale Artikelnummer::
BOSSBS-11678R-CY7
Beschreibung:
Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nuclear pore complex protein Nup107 (Nucleoporin Nup107) is an essential part of the nuclear pore complex which is composed of Nup133, Nup160, Nup107 and Nup96. Nup107 is active in assembling peripheral proteins into this complex. The protein, located on both the nuclear and cytoplasmic sides of the pore, is important in RNA export.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11678R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11678R-A555
Lokale Artikelnummer::
BOSSBS-11678R-A555
Beschreibung:
Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nuclear pore complex protein Nup107 (Nucleoporin Nup107) is an essential part of the nuclear pore complex which is composed of Nup133, Nup160, Nup107 and Nup96. Nup107 is active in assembling peripheral proteins into this complex. The protein, located on both the nuclear and cytoplasmic sides of the pore, is important in RNA export.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11678R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11678R-CY3
Lokale Artikelnummer::
BOSSBS-11678R-CY3
Beschreibung:
Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nuclear pore complex protein Nup107 (Nucleoporin Nup107) is an essential part of the nuclear pore complex which is composed of Nup133, Nup160, Nup107 and Nup96. Nup107 is active in assembling peripheral proteins into this complex. The protein, located on both the nuclear and cytoplasmic sides of the pore, is important in RNA export.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5474R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5474R-A555
Lokale Artikelnummer::
BOSSBS-5474R-A555
Beschreibung:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5474R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5474R-A647
Lokale Artikelnummer::
BOSSBS-5474R-A647
Beschreibung:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4296R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4296R-A488
Lokale Artikelnummer::
BOSSBS-4296R-A488
Beschreibung:
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
VE:
1 * 100 µl
Preis auf Anfrage
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