1,4-Dibromo-3,5-difluorobenzene
Artikel-Nr:
(BOSSBS-5336R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5336R-A555
Lokale Artikelnummer::
BOSSBS-5336R-A555
Beschreibung:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4148R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4148R-A488
Lokale Artikelnummer::
BOSSBS-4148R-A488
Beschreibung:
PKMYT1 is a member of the serine/threonine protein kinase family. It preferentially phosphorylates and inactivates cell division cycle 2 protein (cdc2), and thus acts as a negative regulator of entry into mitosis (G2 to M transition). It mediates phosphorylation of cdc2 predominantly on 'Thr-14' and is also involved in Golgi fragmentation. It may be involved in phosphorylation of cdc2 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. It may be a downstream target of Notch signaling pathway during eye development. PKMYT1 is negatively regulated by hyperphosphorylation during mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4901R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4901R-A647
Lokale Artikelnummer::
BOSSBS-4901R-A647
Beschreibung:
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2945R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2945R-A488
Lokale Artikelnummer::
BOSSBS-2945R-A488
Beschreibung:
Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD01483345-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01483345-5G
Lokale Artikelnummer::
BLDPBD01483345-5G
Beschreibung:
tert-Butyl (2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulphonamido)ethyl)carbamate 95%
VE:
1 * 5 g
Lieferant:
Biotium
Beschreibung:
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Lieferant:
Biotium
Beschreibung:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked α (33-35 kDa) and β (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Lieferant:
Biotium
Beschreibung:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked α (33-35 kDa) and β (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Brom-3,5-dimethyl-1-(2-tetrahydropyranyl)-1H-pyrazol
Artikel-Nr:
(EHERC12726460)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12726460
Lokale Artikelnummer::
EHERC12726460
Beschreibung:
1,4-Dimethylcyclohexan (Gemisch der cis- und trans-Isomeren)
VE:
1 * 0,1 g
Artikel-Nr:
(SIAL186104-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
186104-25G
Lokale Artikelnummer::
SIAL186104-25G
Beschreibung:
3,5-Dimethylpiperidine (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BLDPBD27507-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD27507-250MG
Lokale Artikelnummer::
BLDPBD27507-250MG
Beschreibung:
2-Oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 98%
VE:
1 * 250 mg
Artikel-Nr:
(BNUM0199-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0199-50
Lokale Artikelnummer::
BTIUBNUM0199-50
Beschreibung:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked α (33-35 kDa) and β (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
VE:
1 * 50 µl
Artikel-Nr:
(ACRO255350050)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
255350050
Lokale Artikelnummer::
ACRO255350050
Beschreibung:
Dimethyl-trans-1,2-cyclopropanedicarboxylate 99+%
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-0080R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0080R-CY3
Lokale Artikelnummer::
BOSSBS-0080R-CY3
Beschreibung:
B lymphocytes marker CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0080R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0080R-CY7
Lokale Artikelnummer::
BOSSBS-0080R-CY7
Beschreibung:
B lymphocytes marker CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.
VE:
1 * 100 µl
Preis auf Anfrage
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