Suche >
1,4-Dibromo-3,5-difluorobenzene
Drucken
Sie suchten nach:
41 632 results were found
1,4-Dibromo-3,5-difluorobenzene
Lieferant:
FLUOROCHEM
Beschreibung:
2-(3,5-Dimethyl-1H-pyrazol-4-yl)benzoesäure
Artikel-Nr:
(USBI167993)
Lieferant:
US Biological
Hersteller-Artikelnummer::
167993
Lokale Artikelnummer::
USBI167993
Beschreibung:
Anti-WDR35 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Lieferant:
JULABO GmbH
Beschreibung:
Kompakter Kälte-/Wärme-Umwälzthermostat für die Verwendung als Tischgerät oder in einem Abzug; ideal zur Temperierung eines Destillationsgeräts oder einer Miniplant-Installation. Alle vier Modelle haben Pumpenanschlüsse für externe Temperaturanwendungen und eine Badöffnung für die Temperierung kleiner Objekte direkt im Thermostatbad. Aufgrund der maximalen Umgebungstemperatur von +40 °C und der Luftkühlung kann das Gerät neben anderen Geräten oder direkt in einem Abzug platziert werden.
Lieferant:
JULABO GmbH
Beschreibung:
The powerful and robust CORIO™ laboratory circulators provide the exact temperature, absolute precision and a wide working temperature range. The CORIO™ C immersion circulator is the basic model, it is ideal for standard internal applications, the CD model is more advanced and can used for temperature control of external applications if required. The jet nozzle allows continuous adjustment of the pump stream in the bath. The stainless steel baths are durable and have an integrated drain tap (except B5). These open heating bath circulators are ideal for temperature control of samples, preparation of samples for serology and clinical chemistry, analysis, and material testing. The CD-B units are ideal for external temperature control applications in combination with measuring instruments, measuring cells, photometers, refractometers and polarimeters.
Artikel-Nr:
(BLDPBD228385-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD228385-25G
Lokale Artikelnummer::
BLDPBD228385-25G
Beschreibung:
1-Methyl-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester 98%
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-4296R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4296R-HRP
Lokale Artikelnummer::
BOSSBS-4296R-HRP
Beschreibung:
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2423R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2423R-HRP
Lokale Artikelnummer::
BOSSBS-2423R-HRP
Beschreibung:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13300R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13300R-CY5
Lokale Artikelnummer::
BOSSBS-13300R-CY5
Beschreibung:
GBE1 is a 702 amino acid protein that is expressed at high levels in muscle and liver and is involved in glycogen biosynthesis. Existing as a monomer, GBE1 catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on a neighboring glycogen chain and, via this catalytic activity, plays an essential role in glycogen accumulation. Defects in the gene encoding GBE1 are the cause of glycogen storage disease type 4 (GSD4) and adult polyglucosan body disease (APBD), the first of which is a metabolic disorder that is associated with the accumulation of polysaccharides and is characterized by liver disease during childhood. Unlike GSD4, APBD is a late-onset disorder that affects the central and peripheral nervous systems and is characterized by cognitive impairment, pyramidal tetraparesis and peripheral neuropathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13300R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13300R-A555
Lokale Artikelnummer::
BOSSBS-13300R-A555
Beschreibung:
GBE1 is a 702 amino acid protein that is expressed at high levels in muscle and liver and is involved in glycogen biosynthesis. Existing as a monomer, GBE1 catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on a neighboring glycogen chain and, via this catalytic activity, plays an essential role in glycogen accumulation. Defects in the gene encoding GBE1 are the cause of glycogen storage disease type 4 (GSD4) and adult polyglucosan body disease (APBD), the first of which is a metabolic disorder that is associated with the accumulation of polysaccharides and is characterized by liver disease during childhood. Unlike GSD4, APBD is a late-onset disorder that affects the central and peripheral nervous systems and is characterized by cognitive impairment, pyramidal tetraparesis and peripheral neuropathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15165R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15165R-A555
Lokale Artikelnummer::
BOSSBS-15165R-A555
Beschreibung:
C3orf14 (chromosome 3 open reading frame 14), also known as HT021, is a 128 amino acid protein that is encoded by a gene mapping to human chromosome 3p14.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4715R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4715R
Lokale Artikelnummer::
BOSSBS-4715R
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11705R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11705R-CY5
Lokale Artikelnummer::
BOSSBS-11705R-CY5
Beschreibung:
AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumor suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), implicating a role for AIP1 fusion proteins in tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13727R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13727R-CY7
Lokale Artikelnummer::
BOSSBS-13727R-CY7
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB14 (Protocadherin beta 14) is a 798 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whos genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB14) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB14 is a single-pass type I membrane protein that contains six cadherin domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3769R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R-CY3
Lokale Artikelnummer::
BOSSBS-3769R-CY3
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13324R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13324R-CY3
Lokale Artikelnummer::
BOSSBS-13324R-CY3
Beschreibung:
Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8592R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8592R-CY3
Lokale Artikelnummer::
BOSSBS-8592R-CY3
Beschreibung:
Rad and Gem related GTP binding protein (REM) is a member of the RGK subfamily of Ras-like GTPases that also includes Rad, REM2 and Gem/Kir. REM is a phosphorylated protein that is highly expressed in cardiac muscle and moderately expressed in lung, kidney and skeletal muscle. REM associates with several 14-3-3 isoforms as well as with calmodulin in a calcium-dependent manner. REM mediates two distinct signal transduction pathways that regulate both cytoskeletal reorganization and voltage-gated calcium channel activity. REM decreases the current that passes through cardiac voltage-gated L-type Ca channels (Ca(V)). Overexpression of REM may result in the development of cytoplasmic processes, reorganization of the Actin cytoskeleton, reduction in focal adhesion size and an elongated or dendritic-like cell morphology.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
