1,4-Dimethyl-2,5-diphenylbenzene
Artikel-Nr:
(BOSSBS-2423R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2423R-A680
Lokale Artikelnummer::
BOSSBS-2423R-A680
Beschreibung:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterised by muscle hypertrophy and decreased fat mass.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
sec-Butyllithium 1.4 mol/l in Cyclohexan, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-9681R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9681R
Lokale Artikelnummer::
BOSSBS-9681R
Beschreibung:
C19orf45 is a 505 amino acid protein that is encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.
VE:
1 * 100 µl
Artikel-Nr:
(BSENC-1526-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1526-500
Lokale Artikelnummer::
BSENC-1526-500
Beschreibung:
CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. FUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Nervous system. PHARMACEUTICAL: CNTF is being tested under the name Axokine by Regeneron Pharmaceuticals for treatment of human motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). As it induces substantial weight loss, preferentially of fat as opposed to lean body mass, it is being used for obesity treatment. SIMILARITY: Belongs to the CNTF family.
VE:
1 * 500 µl
Artikel-Nr:
(BOSSBS-9190R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-A488
Lokale Artikelnummer::
BOSSBS-9190R-A488
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9190R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-A350
Lokale Artikelnummer::
BOSSBS-9190R-A350
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9190R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-FITC
Lokale Artikelnummer::
BOSSBS-9190R-FITC
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(SIALD76722-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D76722-25G
Lokale Artikelnummer::
SIALD76722-25G
Beschreibung:
Terephthalonitril, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
GRANT INSTRUMENTS
Beschreibung:
Sortiment von digitalen Wasserbädern ohne Rührfunktion mit Kapazitäten von 5 bis 18 Litern. Alle Einheiten haben Edelstahltanks und langlebige lackierte Stahlgehäuse, bieten schnelle Aufheizzeiten, eine gute Temperaturkontrolle, eine Verriegelung an der Vorderseite, benutzerfreundliche Bedienelemente und eine helle, übersichtliche Anzeige. Alle Bäder sind mit Heizmattentechnologie für einen optimalen Arbeitsbereich ausgestattet, und ohne Heizelement im Tank sind sie leichter zu reinigen. Das Sortiment ist ideal für den Einsatz in Bildung und Ausbildung sowie in industriellen Anwendungen wie der Produkt- und Materialprüfung.
Artikel-Nr:
(BLEG760604)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
760604
Lokale Artikelnummer::
BLEG760604
Beschreibung:
Mouse Recombinant BMP-14 (GDF-5) (from E. coli)
VE:
1 * 25 µG
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Artikel-Nr:
(EHERL20421400AL)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L20421400AL
Lokale Artikelnummer::
EHERL20421400AL
Beschreibung:
Organic Standard, 1,4-Dichlornaphthalin 10 µg/ml in Acetonitril, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(EHERL12372000IO)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L12372000IO
Lokale Artikelnummer::
EHERL12372000IO
Beschreibung:
Organic Standard, 1,4-Dichlorbenzol 10 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(ABNOPAB9657)
Lieferant:
Abnova
Hersteller-Artikelnummer::
PAB9657
Lokale Artikelnummer::
ABNOPAB9657
Beschreibung:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of 14-3-3 protein.
VE:
1 * 100 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
1,2-Bis(dimethylphosphino)ethan, Sigma-Aldrich®
Artikel-Nr:
(8.14160.0025)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.14160.0025
Lokale Artikelnummer::
MERC8.14160.0025
Beschreibung:
2,5-Piperazindion zur Synthese, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-5474R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5474R-A555
Lokale Artikelnummer::
BOSSBS-5474R-A555
Beschreibung:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
VE:
1 * 100 µl
Preis auf Anfrage
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