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1,4-Dithian


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Lieferant:  MP Biomedicals
Beschreibung:   Lysing Matrix D is a critical component of FastPrep® sample preparation system. Each impact-resistant 2 ml tube contains 1,4 mm ceramic spheres. Lysing Matrix D tubes have green caps and are found in the FastDNA™ Spin Kit for Plant and Animal Tissues and FastRNA™ Pro Green Kit for isolation of nucleic acids from plants and animals.
Lieferant:  Honeywell Chemicals
Hersteller-Artikelnummer:: 32339H-25KG
Lokale Artikelnummer:: HONC32339H-25KG
Beschreibung:   L(+)-Kaliumnatriumtartrat Tetrahydrat ≥99,5% (durch Perchlorsäure-Titration), Puriss. p.a.
VE:  1 * 25 kg
Artikel-Nr: (MAYBAC13693.50)

Lieferant:  Thermo Scientific
Hersteller-Artikelnummer:: AC13693.50
Lokale Artikelnummer:: MAYBAC13693.50
Beschreibung:   1-(2,3-Xylyl)piperazin
VE:  1 * 50 g
Market Source Item This is a MarketSource item. Additional charges may apply

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-1135R-A680
Lokale Artikelnummer:: BOSSBS-1135R-A680
Beschreibung:   c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labelling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr --> Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:  1 * 100 µl
Artikel-Nr: (662-2874)

Lieferant:  Mettler - Toledo
Hersteller-Artikelnummer:: 51343195
Lokale Artikelnummer:: METT51343195
Beschreibung:   pH-Elektrode mit Glaskörper und S7-Schraubkopf. Empfohlen für Anwendungen, bei denen die Lebensdauer der pH-Elektrode wesentlich kürzer ist als die der Referenzelektrode.
VE: 
Lieferant:  COMBI-BLOCKS
Beschreibung:   2-(Hydroxymethyl)phenylboronsäure
Lieferant:  Mettler - Toledo
Hersteller-Artikelnummer:: 51344163
Lokale Artikelnummer:: METT51344163
Beschreibung:   pH electrodes with MultiPin™ connector.
VE:  1 * 1 ST

Lieferant:  Thermo Orion
Hersteller-Artikelnummer:: 9102BNWP
Lokale Artikelnummer:: ORIO9102BNWP
Beschreibung:   This general purpose pH electrode is ideal for conducting accurate Q.C. and research work.
VE:  1 * 1 ST
Artikel-Nr: (BOSSBS-3353R-CY5.5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3353R-CY5.5
Lokale Artikelnummer:: BOSSBS-3353R-CY5.5
Beschreibung:   Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis. Mediates survival signaling through phosphorylation of BAD, which induces release of the anti-apoptotic protein Bcl-X(L)/BCL2L1. Phosphorylation of MAP3K5, an other proapoptotic protein, by PIM1, significantly decreases MAP3K5 kinase activity and inhibits MAP3K5-mediated phosphorylation of JNK and JNK/p38MAPK subsequently reducing caspase-3 activation and cell apoptosis. Stimulates cell cycle progression at the G1-S and G2-M transitions by phosphorylation of CDC25A and CDC25C. Phosphorylation of CDKN1A, a regulator of cell cycle progression at G1, results in the relocation of CDKN1A to the cytoplasm and enhanced CDKN1A protein stability. Promote cell cycle progression and tumorigenesis by down-regulating expression of a regulator of cell cycle progression, CDKN1B, at both transcriptional and post-translational levels. Phosphorylation of CDKN1B,induces 14-3-3-proteins binding, nuclear export and proteasome-dependent degradation. May affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Acts also as a regulator of homing and migration of bone marrow cells involving functional interaction with the CXCL12-CXCR4 signaling axis.
VE:  1 * 100 µl
Lieferant:  FLUOROCHEM
Beschreibung:   1-(2,4-Xylyl)piperazin

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-279
Lokale Artikelnummer:: PRSI25-279
Beschreibung:   ZNF136 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 14 C2H2-type zinc fingers and 1 KRAB domain. ZNF136 may be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.
VE:  1 * 50 µG
Artikel-Nr: (620-0179)

Lieferant:  AMARELL, ARNO
Hersteller-Artikelnummer:: E908530
Lokale Artikelnummer:: AMARE908530
Beschreibung:   This extremely fast digital thermometer is suitable for industry applications.
VE:  1 * 1 ST
Artikel-Nr: (HONE25508.9025)

Lieferant:  Honeywell Chemicals
Hersteller-Artikelnummer:: 25508.9025
Lokale Artikelnummer:: HONE25508.9025
Beschreibung:   L(+)-Kaliumnatriumtartrat Tetrahydrat
VE:  1 * 25 kg
Lieferant:  FLUOROCHEM
Beschreibung:   1-(2-Hydroxyethyl)imidazol
Lieferant:  MP Biomedicals
Beschreibung:   Potassium sodium tartrate tetrahydrate has been used in organic synthesis to break up emulsions in aqueous workups.
Lieferant:  Sigma-Aldrich
Beschreibung:   Antimon(III)kaliumoxidtartrat Trihydrat 99,0-103,0% (RT), purum p.a., Sigma-Aldrich®
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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