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4-Cyclopropyl-1-fluoro-2-nitrobenzene
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD80 Armenian hamster Monoclonal Antibody [clone: 16-10A1] (PE (Phycoerythrin)/Dazzle™ 594)
Artikel-Nr:
(212-0208)
Lieferant:
KARTELL
Hersteller-Artikelnummer::
1387
Lokale Artikelnummer::
KART1387
Beschreibung:
PMP (TPX®), crystal clear.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-8135R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8135R-CY7
Lokale Artikelnummer::
BOSSBS-8135R-CY7
Beschreibung:
The specific function of CCDC54 (coiled-coil domain containing 54) is not yet known. The CCDC54 gene appears to be conserved in chimpanzee, dog, mouse, and rat.CCDC54, also known as coiled-coil domain-containing protein 54 or testis development protein NYD-SP17, is a 328 amino acid protein that is phosphorylated on threonine 182 during post-translational modification. The gene encoding NYD-SP17 maps to human chromosome 3q13.12 and mouse chromosome 16 B5. Human chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11592R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11592R-HRP
Lokale Artikelnummer::
BOSSBS-11592R-HRP
Beschreibung:
Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1122R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1122R-A555
Lokale Artikelnummer::
BOSSBS-1122R-A555
Beschreibung:
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11592R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11592R-A647
Lokale Artikelnummer::
BOSSBS-11592R-A647
Beschreibung:
Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13244R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13244R-A488
Lokale Artikelnummer::
BOSSBS-13244R-A488
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (i.e. a photon, pheromone, odorant, hormone or neurotransmitter), while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the Beta subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the Gamma as well as the Alpha and Beta subunits, and that preferential associations between members of subunit families increase G protein functional diversity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5828R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5828R-CY3
Lokale Artikelnummer::
BOSSBS-5828R-CY3
Beschreibung:
Cadherins are calcium-dependent cell-cell adhesion molecules, and protocadherins constitute a subfamily of nonclassic cadherins. Protocadherin beta 13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5828R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5828R-A750
Lokale Artikelnummer::
BOSSBS-5828R-A750
Beschreibung:
Cadherins are calcium-dependent cell-cell adhesion molecules, and protocadherins constitute a subfamily of nonclassic cadherins. Protocadherin beta 13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organisation similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
VE:
1 * 100 µl
Artikel-Nr:
(18-1112-53)
Lieferant:
Cytiva
Hersteller-Artikelnummer::
18-1112-53
Lokale Artikelnummer::
GEHE18-1112-53
Beschreibung:
Polyetheretherketone tubing (PEEK) is intended for use with AKTA systems.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI7335P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7335P
Lokale Artikelnummer::
PRSI7335P
Beschreibung:
16 amino acids near the center of human ULK1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7297P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7297P
Lokale Artikelnummer::
PRSI7297P
Beschreibung:
16 amino acid peptide near the amino terminus of human SLC27A6.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7233P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7233P
Lokale Artikelnummer::
PRSI7233P
Beschreibung:
16 amino acid peptide near the center of human IL-15RA.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-524)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-524
Lokale Artikelnummer::
PRSI33-524
Beschreibung:
Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-11771R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11771R-CY5
Lokale Artikelnummer::
BOSSBS-11771R-CY5
Beschreibung:
SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13726R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13726R-CY7
Lokale Artikelnummer::
BOSSBS-13726R-CY7
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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