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1,6-Anhydro-\\u03B2-D-mannopyranose
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1,6-Anhydro-\\u03B2-D-mannopyranose
Artikel-Nr:
(BOSSBS-1472R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1472R-A350
Lokale Artikelnummer::
BOSSBS-1472R-A350
Beschreibung:
Interferon (IFN) Inducible 16 (IFI16) protein belongs to a family of HIN 200 human and mouse proteins. IFI16 is a nuclear protein comtaining regulatory domains such as DNA binding domain, transcriptional regulatory domain and DAPIN/PAAD domain. IFI16 has three isotypes A, B, and C (85-95 kDa), which arise as a result of mRNA alternative splicing. All are phosphorylated on serine and threonine residues and can homo and heterodimerize. Expression is restricted to the nuclei of hematopoietic cells, fibroblasts and epithelial cells. IFI16 expression in hematopoietic cells of myeloid lineage is tightly regulated and highly induced in the differentiation and proliferation of the cell. Due to its localisation in the nucleus, regulation of protein expression, and ability to bind DNA, it is assumed that IFI16 has a role in transcription regulation of cell differentiation. In addition, it was found that IFI16 can act as a transcriptional repressor and is involved in regulation and activation of p53 in cancer cells.
VE:
1 * 100 µl
Lieferant:
Welch by Gardner Denver
Beschreibung:
Ölnebelfilter, OME 10/16, DN 16 KF Anschlussflansch
Artikel-Nr:
(BOSSBS-11138R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11138R-A350
Lokale Artikelnummer::
BOSSBS-11138R-A350
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11483R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11483R-A680
Lokale Artikelnummer::
BOSSBS-11483R-A680
Beschreibung:
Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular semaphorin domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterised by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. SEMA6C, also known as SEMA Y, is a transmembrane protein expressed in fetal brain and adult skeletal muscle. Three isoforms of this semaphorin exist due to alternative splicing: SEMA6C 1, SEMA6C 2 and SEMA6C 3. The extracellular domain of SEMA6C induces growth cone collapse of dorsal root ganglion and plays a role in generation or stability of entorhino-hippocampal synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11138R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11138R-A680
Lokale Artikelnummer::
BOSSBS-11138R-A680
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13319R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13319R-A555
Lokale Artikelnummer::
BOSSBS-13319R-A555
Beschreibung:
Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.
VE:
1 * 100 µl
Artikel-Nr:
(HEWL9301-1379)
Lieferant:
Agilent
Hersteller-Artikelnummer::
9301-1379
Lokale Artikelnummer::
HEWL9301-1379
Beschreibung:
Chromatographieampullen-Verschlüsse, Ø: 16 mm, Schraubverschlüsse, für 6-ml-Fläschchen
VE:
1 * 100 ST
Artikel-Nr:
(ABNORAB01704.100UL)
Lieferant:
Abnova
Hersteller-Artikelnummer::
RAB01704.100UL
Lokale Artikelnummer::
ABNORAB01704.100UL
Beschreibung:
Anti-Cytokeratin 16 Rabbit Recombinant Antibody [clone: R02-5F8]
VE:
1 * 100 µl
Lieferant:
HAMILTON BONADUZ
Beschreibung:
Stainless steel tube adapters, 1/4" - 28 male tube 1/16" O.D.
Artikel-Nr:
(BOSSBS-1472R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1472R-CY3
Lokale Artikelnummer::
BOSSBS-1472R-CY3
Beschreibung:
Interferon (IFN) Inducible 16 (IFI16) protein belongs to a family of HIN 200 human and mouse proteins. IFI16 is a nuclear protein comtaining regulatory domains such as DNA binding domain, transcriptional regulatory domain and DAPIN/PAAD domain. IFI16 has three isotypes A, B, and C (85-95 kDa), which arise as a result of mRNA alternative splicing. All are phosphorylated on serine and threonine residues and can homo and heterodimerize. Expression is restricted to the nuclei of hematopoietic cells, fibroblasts and epithelial cells. IFI16 expression in hematopoietic cells of myeloid lineage is tightly regulated and highly induced in the differentiation and proliferation of the cell. Due to its localisation in the nucleus, regulation of protein expression, and ability to bind DNA, it is assumed that IFI16 has a role in transcription regulation of cell differentiation. In addition, it was found that IFI16 can act as a transcriptional repressor and is involved in regulation and activation of p53 in cancer cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5843R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5843R-FITC
Lokale Artikelnummer::
BOSSBS-5843R-FITC
Beschreibung:
PCDHB11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15316R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15316R-CY5
Lokale Artikelnummer::
BOSSBS-15316R-CY5
Beschreibung:
C9orf16 (chromosome 9 open reading frame 16) is an 83 amino acid protein that belongs to the UPF0184 (EST00098) family and is encoded by a gene that maps to human chromosome 9q34.11. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15429R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15429R-A350
Lokale Artikelnummer::
BOSSBS-15429R-A350
Beschreibung:
HCP5 is a region present on chromosome 6p21.3 that is characterised by multiple duplicated gene families. HCP5 (HLA class I histocompatibility antigen protein P5), also known as P5-1, is a 132 amino acid protein that is encoded by a gene mapping to human chromosome 6p21.33. Localising within the MHC class I region, HCP5 is not structurally related to other MHC class I genes, but does have high sequence similarity with HERV-L and HERV-16. HCP5 also has high sequence homology to retroviral Pol genes, making it a possible candidate for interaction with HIV-1 through an antisense mechanism that prevents retrovirus transcription. Single-nucleotide polymorphisms (SNPs) to the region of the HCP5 gene that corresponds with HLA-B has been linked to a lower HIV-1 viral set point. HCP5 is highly expressed in lymphoid tissues, spleen and activated lymphocytes, as well as B-cell and natural killer (NK) cell lines.
VE:
1 * 100 µl
Lieferant:
Cytiva
Beschreibung:
O-ring, 55×1,6 EPDM
Artikel-Nr:
(USBI044078-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
044078-BIOTIN
Lokale Artikelnummer::
USBI044078-BIOTIN
Beschreibung:
Anti-ZFYVE16 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Lieferant:
Cytiva
Beschreibung:
Y connector, 3×UNF 5/16" female
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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