Suche >
2,4-Dichloro-1-(2-propynyloxy)benzene
Drucken
Sie suchten nach:
61 916 results were found
2,4-Dichloro-1-(2-propynyloxy)benzene
Lieferant:
Alfa Aesar
Beschreibung:
An analog of tacrolimus (FK-506). Ascomycin is an inhibitor of PP2 and it is potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
Artikel-Nr:
(PRSI92-544)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-544
Lokale Artikelnummer::
PRSI92-544
Beschreibung:
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.
VE:
1 * 50 µG
Artikel-Nr:
(MOLE11004673-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
11004673-25G
Lokale Artikelnummer::
MOLE11004673-25G
Beschreibung:
2,3-Dimethoxybenzylalkohol
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(129-0273)
Lieferant:
Texwipe
Hersteller-Artikelnummer::
TX7101
Lokale Artikelnummer::
TEXWTX7101
Beschreibung:
Das ITW Texwipe® Mini AlphaMop™ Isolatorreinigungswerkzeug wurde für die Reinigung von Isolatoren, Biosicherheitsschränken, Handschuhboxen und Werkbankabzügen entwickelt. Der Wischmopp hat eine niedrige, flache Form und abgerundete Ecken. Er besteht aus Celcon® Plastik und ist vollständig autoklavierbar. Durch das Drehgelenk kann der Benutzer auch schwer zugängliche Stellen erreichen. Dank des austauschbaren Schaumstoff-Pads, passt sich der Moppbezug garantiert jeder Reinigungsfläche an. 129-0273 umfasst zwei Stiele, 12 Zoll und 18 Zoll (30,4 and 45,7 cm), und lässt sich mühelos mit einer Hand verwenden.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
N-(2-Bromethyl)phthalimid, Sigma-Aldrich®
Artikel-Nr:
(BOHLC354-05)
Lieferant:
Bohlender
Hersteller-Artikelnummer::
C354-05
Lokale Artikelnummer::
BOHLC354-05
Beschreibung:
PTFE coated stirring bars. Provide excellent centering and smooth stirring.
VE:
1 * 1 ST
Artikel-Nr:
(J62863.22)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J62863.22
Lokale Artikelnummer::
ALFAJ62863.22
Beschreibung:
Ethylorange Natriumsalz
VE:
1 * 100 g
Artikel-Nr:
(SAMC241)
Lieferant:
SAMCO
Hersteller-Artikelnummer::
241
Lokale Artikelnummer::
SAMC241
Beschreibung:
These pipettes made of shatterproof, non toxic PE prevent cross-contamination and are used for blood bank applications such as sedimentation procedures.
VE:
1 * 500 ST
Artikel-Nr:
(REST35021)
Lieferant:
Restek
Hersteller-Artikelnummer::
35021
Lokale Artikelnummer::
REST35021
Beschreibung:
This mixture can be used for quantification (AOCS method CE 1a-13) and approximate the compositions of oils.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-2911R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2911R-CY7
Lokale Artikelnummer::
BOSSBS-2911R-CY7
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF. MAP2K6/MKK6 also phosphorylates and activates PAK6. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Nuclear targets of p38 MAP kinase include the transcription factors ATF2 and ELK1. Within the p38 MAPK signal transduction pathway, MAP3K6/MKK6 mediates phosphorylation of STAT4 through MAPK14 activation, and is therefore required for STAT4 activation and STAT4-regulated gene expression in response to IL-12 stimulation. The pathway is also crucial for IL-6-induced SOCS3 expression and down-regulation of IL-6-mediated gene induction; and for IFNG-dependent gene transcription. Has a role in osteoclast differentiation through NF-kappa-B transactivation by TNFSF11, and in endochondral ossification and since SOX9 is another likely downstream target of the p38 MAPK pathway. MAP2K6/MKK6 mediates apoptotic cell death in thymocytes. Acts also as a regulator for melanocytes dendricity, through the modulation of Rho family GTPases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2911R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2911R-A488
Lokale Artikelnummer::
BOSSBS-2911R-A488
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF. MAP2K6/MKK6 also phosphorylates and activates PAK6. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Nuclear targets of p38 MAP kinase include the transcription factors ATF2 and ELK1. Within the p38 MAPK signal transduction pathway, MAP3K6/MKK6 mediates phosphorylation of STAT4 through MAPK14 activation, and is therefore required for STAT4 activation and STAT4-regulated gene expression in response to IL-12 stimulation. The pathway is also crucial for IL-6-induced SOCS3 expression and down-regulation of IL-6-mediated gene induction; and for IFNG-dependent gene transcription. Has a role in osteoclast differentiation through NF-kappa-B transactivation by TNFSF11, and in endochondral ossification and since SOX9 is another likely downstream target of the p38 MAPK pathway. MAP2K6/MKK6 mediates apoptotic cell death in thymocytes. Acts also as a regulator for melanocytes dendricity, through the modulation of Rho family GTPases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2911R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2911R-HRP
Lokale Artikelnummer::
BOSSBS-2911R-HRP
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF. MAP2K6/MKK6 also phosphorylates and activates PAK6. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Nuclear targets of p38 MAP kinase include the transcription factors ATF2 and ELK1. Within the p38 MAPK signal transduction pathway, MAP3K6/MKK6 mediates phosphorylation of STAT4 through MAPK14 activation, and is therefore required for STAT4 activation and STAT4-regulated gene expression in response to IL-12 stimulation. The pathway is also crucial for IL-6-induced SOCS3 expression and down-regulation of IL-6-mediated gene induction; and for IFNG-dependent gene transcription. Has a role in osteoclast differentiation through NF-kappa-B transactivation by TNFSF11, and in endochondral ossification and since SOX9 is another likely downstream target of the p38 MAPK pathway. MAP2K6/MKK6 mediates apoptotic cell death in thymocytes. Acts also as a regulator for melanocytes dendricity, through the modulation of Rho family GTPases.
VE:
1 * 100 µl
Lieferant:
KIMBERLY CLARK
Beschreibung:
Diese Handschuhe können für die Handhabung von Chemikalien, in der Produktion, Konstruktion und Landwirtschaft, gewerblichen Reinigung und bei hausmeisterlichen Dienstleistungen sowie im öffentlichen Dienst verwendet werden.
Lieferant:
Sigma-Aldrich
Beschreibung:
1-Vinyl-2-pyrrolidon stabilisiert, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-5876R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5876R
Lokale Artikelnummer::
BOSSBS-5876R
Beschreibung:
Matrix Metalloproteinase 28, also known as epilysin, was first cloned from human skin keratinocytes and described to reflect its role in the remodeling of the epidermis. It was found in testis, as well as heart, brain, placenta, lung, prostate, intestine, and colon. MMP28 was later cloned from human lung and found in lung, kidney, brain, skeletal muscle, and several tumor cell lines. At least three MMP28 transcripts of 2.6, 2.0, and 1.2 kb have been reported possibly representing alternatively spliced forms of MMP28. There are two human sequences (isoform1 and isoform 2) which encode proteins of 520 and 393 amino acids with predicted masses of 58.9 and 44.5 kDa respectively. The mouse sequence contains two inserts of 41 and 39 amino acids respectively, relative to the human sequence. Mouse epilysin has a predicted molecular mass of approx. 70 kDa. Mouse and human epilysin are highly conserved and share 97% identical residues. Epilysin (MMP-28) contains the key domains of the other MMPs: a signal peptide, conserved cysteine-containing prodomain (with a furin cleavage site), conserved histidine-containing catalytic domain, hinge domain, and hemopexin domain. MMP28 has a furin cleavage site, similar to MMP11, and is cleaved by the prohormone convertase family of enzymes. Sequence identity between MMP28 and the other MMPs is low overall. MMP28 is most closely related to MMP19 (39% sequence identity). Recombinant MMP28 degrades casein.
VE:
1 * 100 µl
Artikel-Nr:
(LAUDL003510)
Lieferant:
LAUDA
Hersteller-Artikelnummer::
L003510
Lokale Artikelnummer::
LAUDL003510
Beschreibung:
Ultracool circulation chillers provide precise temperature control in an extended operating temperature range from −10 to +35 °C and a temperature stability of ±0,5 K.
VE:
1 * 1 ST
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
