2,2\'-Difluorodiphenyldisulphide
Artikel-Nr:
(EHERYA11949500MB)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
YA11949500MB
Lokale Artikelnummer::
EHERYA11949500MB
Beschreibung:
Organic Standard, 2,2-Dichlorpropionsäure 1.000 µg/ml in tert-Butylmethylether, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-15350R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15350R-CY3
Lokale Artikelnummer::
BOSSBS-15350R-CY3
Beschreibung:
C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI6057P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6057P
Lokale Artikelnummer::
PRSI6057P
Beschreibung:
SHISA9 peptide is used for blocking the activity of SHISA9 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-12495R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-A350
Lokale Artikelnummer::
BOSSBS-12495R-A350
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A350
Lokale Artikelnummer::
BOSSBS-13343R-A350
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-CY7
Lokale Artikelnummer::
BOSSBS-13343R-CY7
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(PROOCIL-PCB-99-CS)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-99-CS
Lokale Artikelnummer::
PROOCIL-PCB-99-CS
Beschreibung:
Organic Standard, 2,2',4,4',5-Pentachlorbiphenyl (PCB Nr. 99) 100 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1,2 mL
Artikel-Nr:
(PROOCIL-PCB-44-CS)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-44-CS
Lokale Artikelnummer::
PROOCIL-PCB-44-CS
Beschreibung:
Organic Standard, 2,2',3,5'-Tetrachlorbiphenyl (PCB Nr. 44) 100 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1,2 mL
Artikel-Nr:
(PROOCIL-PCB-84)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-84
Lokale Artikelnummer::
PROOCIL-PCB-84
Beschreibung:
Organic Standard, 2,2',3,3',6-Pentachlorbiphenyl (PCB Nr. 84) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-92)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-92
Lokale Artikelnummer::
PROOCIL-PCB-92
Beschreibung:
Organic Standard, 2,2',3,5,5'-Pentachlorbiphenyl (PCB Nr. 92) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-47)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-47
Lokale Artikelnummer::
PROOCIL-PCB-47
Beschreibung:
Organic Standard, 2,2',4,4'-Tetrachlorbiphenyl (PCB Nr. 47) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-186)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-186
Lokale Artikelnummer::
PROOCIL-PCB-186
Beschreibung:
Organic Standard, 2,2',3,4,5,6,6'-Heptachlorbiphenyl (PCB Nr. 186) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-86)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-86
Lokale Artikelnummer::
PROOCIL-PCB-86
Beschreibung:
Organic Standard, 2,2',3,4,5-Pentachlorbiphenyl (PCB Nr. 86) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-83)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-83
Lokale Artikelnummer::
PROOCIL-PCB-83
Beschreibung:
Organic Standard, 2,2',3,3',5-Pentachlorbiphenyl (PCB Nr. 83) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-101-CS)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-101-CS
Lokale Artikelnummer::
PROOCIL-PCB-101-CS
Beschreibung:
Organic Standard, 2,2',4,5,5'-Pentachlorbiphenyl (PCB Nr. 101) 100 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1,2 mL
Artikel-Nr:
(PROOCIL-PCB-152)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-152
Lokale Artikelnummer::
PROOCIL-PCB-152
Beschreibung:
Organic Standard, 2,2',3,5,6,6'-Hexachlorbiphenyl (PCB Nr. 152) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
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