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2,2-Dimethylbut-3-ynoic+acid
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2,2-Dimethylbut-3-ynoic+acid
Artikel-Nr:
(PRSI26-396)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-396
Lokale Artikelnummer::
PRSI26-396
Beschreibung:
PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 50 µG
Artikel-Nr:
(HUBE2041.0001.01)
Lieferant:
HUBER
Hersteller-Artikelnummer::
2041.0001.01
Lokale Artikelnummer::
HUBE2041.0001.01
Beschreibung:
BFT5 is a special heating and cooling thermostat ideal for beer-forcing test. This unit is fitted with True Adaptive temperature control and programmer for automatic temperature cycles. The beer is artificially ages with changing temperature between 0 and 60 °C in a 24 hour cycle. The unit features a pressure suction pump, programmer with calender and clock function.
VE:
1 * 1 ST
Artikel-Nr:
(REST31903)
Lieferant:
Restek
Hersteller-Artikelnummer::
31903
Lokale Artikelnummer::
REST31903
Beschreibung:
Consists of 47 components, those are acenaphthene, acenaphthylene, acetophenone, anthracene, benzanthracene, benzopyrene, benzofluoranthene, benzoperylene, benzofluoranthene, benzyl butyl phthalate, biphenyl, bismethane, bisether, bisphthalate, 4-bromophenyl phenyl ether, carbazole, 4-chloroaniline, 2-chloronaphthalene, 4-chlorophenyl phenyl ether, chrysene, dibenzanthracene, dibenzofuran, diethylphthalate, dimethylphthalate, di-n-butyl phthalate, 2,4-dinitrotoluene, 2,6-dinitrotoluene, di-n-octyl phthalate, diphenylamine *,fluoranthene, fluorene, hexachlorobenzene, hexachloro-1,3-butadiene , hexachlorocyclopentadiene, hexachloroethane, indenopyrene, isophorone, 2-methylnaphthalene, naphthalene, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, nitrobenzene, n-nitroso-di-n-propylamine, 2,2'-oxybis, phenanthrene and pyrene.
VE:
1 * 1 Ampull
Artikel-Nr:
(BOSSBS-1865R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1865R-CY5
Lokale Artikelnummer::
BOSSBS-1865R-CY5
Beschreibung:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognized by HDAC6, leading to their recruitment to aggresomes, followed by degradation. Mediates 'Lys-63'-linked polyubiquitination of SNCAIP, possibly playing a role in Lewy-body formation. Mediates monoubiquitination of BCL2, thereby acting as a positive regulator of autophagy. Promotes the autophagic degradation of dysfunctional depolarized mitochondria (mitophagy) by the ubiquitination of mitochondrial proteins such as TOMM2, RHOT1/MIRO1 and USP3 (PubMed:24896179). Mediates 'Lys-48'-linked polyubiquitination of ZNF746, followed by degradation of ZNF746 by the proteasome; possibly playing a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene.
VE:
1 * 100 µl
Lieferant:
Binder
Beschreibung:
Die Avantgarde.Line-Geräte der M-Serie verfügen über eine maximale Temperatur von 300 °C und verschiedene erweiterte Programmieroptionen machen diese Materialprüfkammern ideal für Material- und Alterungstests. Die Geräte verfügen über einen hohen Luftdurchsatz und ihre leistungsstarken Ventilatoren sorgen für eine schnelle Erwärmung.
Artikel-Nr:
(PRSI26-398)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-398
Lokale Artikelnummer::
PRSI26-398
Beschreibung:
PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1865R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1865R-A488
Lokale Artikelnummer::
BOSSBS-1865R-A488
Beschreibung:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognized by HDAC6, leading to their recruitment to aggresomes, followed by degradation. Mediates 'Lys-63'-linked polyubiquitination of SNCAIP, possibly playing a role in Lewy-body formation. Mediates monoubiquitination of BCL2, thereby acting as a positive regulator of autophagy. Promotes the autophagic degradation of dysfunctional depolarized mitochondria (mitophagy) by the ubiquitination of mitochondrial proteins such as TOMM2, RHOT1/MIRO1 and USP3 (PubMed:24896179). Mediates 'Lys-48'-linked polyubiquitination of ZNF746, followed by degradation of ZNF746 by the proteasome; possibly playing a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene.
VE:
1 * 100 µl
Artikel-Nr:
(MOLEM23033641)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M23033641
Lokale Artikelnummer::
MOLEM23033641
Beschreibung:
Dibenzo-30-krone-10 (Dibenzo-1,4,7,10,13,16,19,22,25,28-decaoxacyclotriacontan)
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
NICKEL ELECTRO
Beschreibung:
These circulating water baths are available in two ranges for circulating just water up to 99 °C or oil up to 130 °C. Operating temperatures below ambient can be achieved using an optional refrigerated dip cooler. Units have touch pad controls with easy wipe clean fronts which are chemical resistant and splash proof.
Artikel-Nr:
(SIAL331449-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
331449-25G
Lokale Artikelnummer::
SIAL331449-25G
Beschreibung:
3-Amino-5-hydroxy-1H-pyrazol, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
VACUUBRAND
Beschreibung:
Diese Chemie-Vakuumsysteme können für eine Vielzahl von Anwendungen in Chemie- und Physiklaboren eingesetzt werden, um Gase und Dämpfe zu evakuieren und zwischen verschiedenen Gefäßen zu fördern, z.B. als Alternative zu Wasserstrahlpumpen und Drehschieberpumpen. Kompakte Konstruktion, sehr leiser Betrieb, lange Lebensdauer; sehr einfacher Wechsel der Membranen und Ventile. Ölfreies Vakuum.
Lieferant:
MOTIC
Beschreibung:
The Panthera TEC POL models present a high flexibility for the inspection of all kind of polarizing materials, for transparent samples like fibers and foils with their inherent birefringence, as well as for opaque specimen from education environment and industrial quality control.
Lieferant:
Sigma-Aldrich
Beschreibung:
Guanosin-5'-diphosphat Natriumsalz, Sigma-Aldrich®
Artikel-Nr:
(PRSI91-327)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-327
Lokale Artikelnummer::
PRSI91-327
Beschreibung:
T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
VE:
1 * 50 µG
Lieferant:
BARNSTEAD THERMOLYNE
Beschreibung:
The Barnstead Smart2Pure™ system is a compact system that converts tap water into both ASTM Type I and Type II water. It produces 3 or 6 liters of ultra-pure water per hour.
Artikel-Nr:
(331-4172)
Lieferant:
GREINER BIO ONE
Hersteller-Artikelnummer::
450075_2000
Lokale Artikelnummer::
GREI450075_2000
Beschreibung:
These needles are designed for blood collection procedures.
VE:
1 * 2.000 ST
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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