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2,2-Diphenyl-1-picrylhydrazyl+(free+radical)
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2,2-Diphenyl-1-picrylhydrazyl+(free+radical)
Artikel-Nr:
(BOSSBS-8389R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8389R-A350
Lokale Artikelnummer::
BOSSBS-8389R-A350
Beschreibung:
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8389R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8389R-FITC
Lokale Artikelnummer::
BOSSBS-8389R-FITC
Beschreibung:
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM1094-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1094-50
Lokale Artikelnummer::
BTIUBNUM1094-50
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
VE:
1 * 50 µl
Artikel-Nr:
(BNUM0459-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0459-50
Lokale Artikelnummer::
BTIUBNUM0459-50
Beschreibung:
This MAb reacts with a protein of 22 kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
VE:
1 * 50 µl
Artikel-Nr:
(BNUM0211-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0211-50
Lokale Artikelnummer::
BTIUBNUM0211-50
Beschreibung:
This MAb reacts with a protein of 22 kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
VE:
1 * 50 µl
Artikel-Nr:
(BTIUBNUM0247-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0247-50
Lokale Artikelnummer::
BTIUBNUM0247-50
Beschreibung:
This MAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-1874R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1874R-A680
Lokale Artikelnummer::
BOSSBS-1874R-A680
Beschreibung:
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
It acts as a mild and selective oxidizing agent in organic synthesis and materials science. Manganese(III) Acetate Dihydrate is also a reagent used for radical cyclizations and α-keto-acetoxylation.
Artikel-Nr:
(BOSSBS-1874R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1874R-HRP
Lokale Artikelnummer::
BOSSBS-1874R-HRP
Beschreibung:
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1874R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1874R-A350
Lokale Artikelnummer::
BOSSBS-1874R-A350
Beschreibung:
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1874R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1874R-A488
Lokale Artikelnummer::
BOSSBS-1874R-A488
Beschreibung:
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0027-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0027-50
Lokale Artikelnummer::
BTIUBNUM0027-50
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. Epitope of MAb Bra7G is clearly different from that of MAb DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
VE:
1 * 50 µl
Artikel-Nr:
(BNUM0054-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0054-50
Lokale Artikelnummer::
BTIUBNUM0054-50
Beschreibung:
This MAb reacts with a protein of 22 kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
VE:
1 * 50 µl
Artikel-Nr:
(BNUM0302-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0302-50
Lokale Artikelnummer::
BTIUBNUM0302-50
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop V). Epitope of MAb Bra7G is clearly different from that of MAb DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-12390R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12390R-A647
Lokale Artikelnummer::
BOSSBS-12390R-A647
Beschreibung:
Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12390R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12390R-A350
Lokale Artikelnummer::
BOSSBS-12390R-A350
Beschreibung:
Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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