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1-Boc-3-ethynyl-3-hydroxyazetidine
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1-Boc-3-ethynyl-3-hydroxyazetidine
Artikel-Nr:
(BOSSBS-12402R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12402R-CY7
Lokale Artikelnummer::
BOSSBS-12402R-CY7
Beschreibung:
RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13283R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13283R-FITC
Lokale Artikelnummer::
BOSSBS-13283R-FITC
Beschreibung:
GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13265R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13265R-A647
Lokale Artikelnummer::
BOSSBS-13265R-A647
Beschreibung:
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
VE:
1 * 100 µl
Artikel-Nr:
(BTIUBNUM0956-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0956-50
Lokale Artikelnummer::
BTIUBNUM0956-50
Beschreibung:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-1350R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-CY7
Lokale Artikelnummer::
BOSSBS-1350R-CY7
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-A647
Lokale Artikelnummer::
BOSSBS-1350R-A647
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15401R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15401R-A647
Lokale Artikelnummer::
BOSSBS-15401R-A647
Beschreibung:
H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R-A488
Lokale Artikelnummer::
BOSSBS-13314R-A488
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8582R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8582R-CY5
Lokale Artikelnummer::
BOSSBS-8582R-CY5
Beschreibung:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. GTDC1 (Glycosyltransferase-like domain-containing protein 1), also known as Mat-Xa, is a 458 amino acid protein belonging to the glycosyltransferase 1 family. GTDC1 is ubiquitously expressed, with highest levels found in peripheral blood leukocytes, spleen, lung and testis.An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11043R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11043R-A555
Lokale Artikelnummer::
BOSSBS-11043R-A555
Beschreibung:
Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-A350
Lokale Artikelnummer::
BOSSBS-8345R-A350
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9368R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9368R-CY7
Lokale Artikelnummer::
BOSSBS-9368R-CY7
Beschreibung:
OCEL1, is a 264 amino acid protein that is encoded by a gene which maps to human chromosome 19. Chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11802R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11802R-FITC
Lokale Artikelnummer::
BOSSBS-11802R-FITC
Beschreibung:
The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-D is a 710 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-D mediates the Na+-independent transport of vasopressin, prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II and other organic anions, but not estrone-3-sulfate, DPDPE, taurocholate, DHEAS or digoxin. OATP-D is ubiquitously expressed with highest levels present in leukocytes and spleen. OATP-D is expressed as four isoforms produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11629R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11629R-A647
Lokale Artikelnummer::
BOSSBS-11629R-A647
Beschreibung:
Olfactory receptors are G protein-coupled receptors that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction that propagates nerve impulses throughout the body, ultimately leading to transmission of the signal to the brain and the subsequent perception of smell. OR10J3 (olfactory receptor 10J3) is a 329 amino acid protein. The gene encoding OR10J3 maps to human chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8211R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8211R-CY5
Lokale Artikelnummer::
BOSSBS-8211R-CY5
Beschreibung:
FAM84B, also known as NSE2 or BCMP101, is a 310 amino acid protein that is expressed in esophageal squamous cell carcinomas, suggesting a role in tumor development and metastasis. The gene encoding FAM84B maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11802R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11802R-CY7
Lokale Artikelnummer::
BOSSBS-11802R-CY7
Beschreibung:
The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-D is a 710 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-D mediates the Na+-independent transport of vasopressin, prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II and other organic anions, but not estrone-3-sulfate, DPDPE, taurocholate, DHEAS or digoxin. OATP-D is ubiquitously expressed with highest levels present in leukocytes and spleen. OATP-D is expressed as four isoforms produced by alternative splicing events.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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