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2-(1H-Imidazol-1-yl)isonicotinic+acid
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2-(1H-Imidazol-1-yl)isonicotinic+acid
Lieferant:
MP Biomedicals
Beschreibung:
Storage: Store at +4 °C, store under nitrogen
Glutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione. Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
Artikel-Nr:
(PRSI92-083)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-083
Lokale Artikelnummer::
PRSI92-083
Beschreibung:
Carbonic Anhydrase 3 (CA3) belongs to the Alpha-Carbonic Anhydrase family that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyse the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and it is present at high levels in skeletal muscle with much lower levels found in cardiac and smooth muscle. CA3 is activated by proton donors such as imidazole and the dipeptide histidylhistidine. CA3 is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.
VE:
1 * 50 µG
Artikel-Nr:
(PIER46425)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
46425
Lokale Artikelnummer::
PIER46425
Beschreibung:
FITC (Fluorescein-5-isothiocyanat, Fluoresceinisothiocyanat Isomer I)
VE:
1 * 100 mg
Artikel-Nr:
(PIER46424)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
46424
Lokale Artikelnummer::
PIER46424
Beschreibung:
FITC (Fluorescein-5-isothiocyanat, Fluoresceinisothiocyanat Isomer I)
VE:
1 * 1 g
Artikel-Nr:
(MOLE43825432-1G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
43825432-1G
Lokale Artikelnummer::
MOLE43825432-1G
Beschreibung:
FITC (Fluorescein-5-isothiocyanat, Fluoresceinisothiocyanat Isomer I)
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Fluorescein isothiocyanate (FITC) is widely used to attach a fluorescent label to proteins via the amine group. The isothiocyanate group reacts with amino terminal and primary amines in proteins. It has been used for the labeling of proteins including antibodies and lectins. Fluorescein isothiocyanate isomer I has been used for the staining of conidia.
Reagent for the FITC labeling of proteins; Microsequencing of proteins and peptides (HPLC).
Artikel-Nr:
(GRNB11711704)
Lieferant:
GREINER BIOCHEMICAL
Hersteller-Artikelnummer::
11711704
Lokale Artikelnummer::
GRNB11711704
Beschreibung:
Creatinin
VE:
1 * 1 KIT
Lieferant:
Thermo Scientific
Beschreibung:
This antibody labeling system uses nickel chelated agarose to temporarily immobilise antibody molecules via their histidine-rich Fc regions. Once held in place on the gel, the antibody can be biotinylated at either sulfhydryl groups (after mild reduction or disulfide bonds) or primary amines. Excess labeling reagent and by-products are then washed away before recovering the labeled and purified antibody from the gel using a mild imidazole solution. No gel filtration or dialysis are needed.
Lieferant:
MP Biomedicals
Beschreibung:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Artikel-Nr:
(8.07572.0025)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.07572.0025
Lokale Artikelnummer::
MERC8.07572.0025
Beschreibung:
1H-Pyrazol zur Synthese, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(8.43855.0005)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.43855.0005
Lokale Artikelnummer::
MERC8.43855.0005
Beschreibung:
3-Phenyl-1H-pyrazol zur Synthese, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
Merck
Beschreibung:
3-Amino-1H-1,2,4-triazol, Sigma-Aldrich®
Lieferant:
Merck
Beschreibung:
5-(Ethylthio)-1H-tetrazol (ETT) 0.25 M in Acetonitril, Novabiochem® Aktivatorlösung
Lieferant:
Merck
Beschreibung:
1,3-Dimethyltetrahydro-2(1H)-pyrimidinon, Sigma-Aldrich®
Artikel-Nr:
(HONC34433-500ML)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
34433-500ML
Lokale Artikelnummer::
HONC34433-500ML
Beschreibung:
Anolyte for coulometric Karl Fischer titration, for cells with and without diaphragm, Methanol-based, free of Imidazole (free of CMR substances).
VE:
1 * 500 mL
Lieferant:
Honeywell Chemicals
Beschreibung:
Medium for volumetric two-component Karl Fischer titration (ethanol or methanol based), Free of imidazole (free of CMR substances)
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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