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5-Chlorobenzo[b]thiophene-3-acetic+acid
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5-Chlorobenzo[b]thiophene-3-acetic+acid
Artikel-Nr:
(BOSSBS-11733R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-CY3
Lokale Artikelnummer::
BOSSBS-11733R-CY3
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11861R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11861R-CY3
Lokale Artikelnummer::
BOSSBS-11861R-CY3
Beschreibung:
HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
VE:
1 * 100 µl
Artikel-Nr:
(COBBOS-1034-100G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
OS-1034-100G
Lokale Artikelnummer::
COBBOS-1034-100G
Beschreibung:
1-Brom-3,5-di-tert-butylbenzol
VE:
1 * 100 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(STRE65-8000-1G)
Lieferant:
Strem Chemicals, Inc.
Hersteller-Artikelnummer::
65-8000-1G
Lokale Artikelnummer::
STRE65-8000-1G
Beschreibung:
Metal Beta-diketonates, Metal TMHD, Volatile Precursors for CVD
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Lieferant:
Strem Chemicals, Inc.
Beschreibung:
Metal Beta-diketonates, Metal TMHD, Volatile Precursors for CVD
Artikel-Nr:
(1604563.)
Lieferant:
USP
Hersteller-Artikelnummer::
1604563
Lokale Artikelnummer::
USPH1604563
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 20 mg
Lieferant:
COMBI-BLOCKS
Beschreibung:
(1-(tert-Butoxycarbonyl)-3,5-dimethyl-1H-pyrazol-4-yl)boronic acid
Artikel-Nr:
(BOSSBS-8262R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8262R-CY3
Lokale Artikelnummer::
BOSSBS-8262R-CY3
Beschreibung:
DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL441783-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
441783-100G
Lokale Artikelnummer::
SIAL441783-100G
Beschreibung:
Hindered phenolic antioxidant for polymers.
VE:
1 * 100 g
Lieferant:
Strem Chemicals, Inc.
Beschreibung:
Metal Beta-diketonates, Metal TMHD, Volatile Organometallics for CVD & ALD, Volatile Precursors for CVD
Artikel-Nr:
(PROOCIL-PCB-35)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-35
Lokale Artikelnummer::
PROOCIL-PCB-35
Beschreibung:
Organic Standard, 3,3',4-Trichlorbiphenyl (PCB Nr. 35) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(USBI041368)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041368
Lokale Artikelnummer::
USBI041368
Beschreibung:
Anti-S35E2 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Lieferant:
Bernd Kraft
Beschreibung:
Wasserstoffperoxid 35%, technische Qualität
Lieferant:
Cayman Chemical
Beschreibung:
Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 µM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 µg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.
Artikel-Nr:
(BOSSBS-9084R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9084R-FITC
Lokale Artikelnummer::
BOSSBS-9084R-FITC
Beschreibung:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6514R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6514R-CY5
Lokale Artikelnummer::
BOSSBS-6514R-CY5
Beschreibung:
CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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