4-Brom-2-(cyclopentyloxy)anisol
Lieferant:
KOEHLER TECHNISCHE PRODUKTEN
Beschreibung:
Acryl
Lieferant:
Thermo Fisher Scientific
Beschreibung:
Automated nucleic acid purification system, accessory, KingFisher™ Duo Prime 12 Well-Elutionsstreifen
Artikel-Nr:
(CHMPFL5486.1)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL5486.1
Lokale Artikelnummer::
CHMPFL5486.1
Beschreibung:
3,4,5-Trifluor-o-phenylendiamin
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-13140R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-A680
Lokale Artikelnummer::
BOSSBS-13140R-A680
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(ABNOMAB2225)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB2225
Lokale Artikelnummer::
ABNOMAB2225
Beschreibung:
Mouse monoclonal antibody raised against Imipramine.
VE:
1 * 100 µG
Artikel-Nr:
(ABNOMAB2246)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB2246
Lokale Artikelnummer::
ABNOMAB2246
Beschreibung:
Mouse monoclonal antibody raised against Phenytoin.
VE:
1 * 100 µG
Artikel-Nr:
(LPIT110511)
Lieferant:
LP ITALIANA
Hersteller-Artikelnummer::
110511
Lokale Artikelnummer::
LPIT110511
Beschreibung:
Küvetten für Sherwood-Typ Kuagulometer
VE:
1 * 1.000 ST
Artikel-Nr:
(BOSSBS-9461R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9461R-A647
Lokale Artikelnummer::
BOSSBS-9461R-A647
Beschreibung:
The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3626R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3626R-CY7
Lokale Artikelnummer::
BOSSBS-3626R-CY7
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3730R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R-CY7
Lokale Artikelnummer::
BOSSBS-3730R-CY7
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(EHERC12333400)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12333400
Lokale Artikelnummer::
EHERC12333400
Beschreibung:
3,4-Dichloranisol
VE:
1 * 0,1 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Brenzcatechin, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
N-Boc-ethylendiamin
Lieferant:
Integra
Beschreibung:
Vacuum aspiration system accessory, Schlauchset bestehend aus VACUSIP Handoperator, Silikonschlauch (1,2 m und 0,22 m) und Filter (nicht steril, 0,45 µm)
Artikel-Nr:
(SIAL61941-1ML-F)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
61941-1ML-F
Lokale Artikelnummer::
SIAL61941-1ML-F
Beschreibung:
Ethylenglycol 5 mol/l in wässriger Lösung, Millipore®
VE:
1 * 1 mL
Artikel-Nr:
(FLUO008552-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
008552-5G
Lokale Artikelnummer::
FLUO008552-5G
Beschreibung:
4,4'-Difluorbenzil
VE:
1 * 5 g
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