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2-(3-Methoxyallylidene)malonic+acid+dimethyl+ester
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2-(3-Methoxyallylidene)malonic+acid+dimethyl+ester
Artikel-Nr:
(BOSSBS-3730R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R-A555
Lokale Artikelnummer::
BOSSBS-3730R-A555
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
Artikel-Nr:
(BOSSBS-3730R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R-A488
Lokale Artikelnummer::
BOSSBS-3730R-A488
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(MOLE25275246-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
25275246-25G
Lokale Artikelnummer::
MOLE25275246-25G
Beschreibung:
Kristallviolett
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(SIAL149209-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
149209-100G
Lokale Artikelnummer::
SIAL149209-100G
Beschreibung:
Methylmethoxyacetat, Sigma-Aldrich®
VE:
1 * 100 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Ethylnitroacetat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
1,2-Bis(dimethylphosphino)ethan, Sigma-Aldrich®
Lieferant:
GE Healthcare - Whatman
Beschreibung:
Whatman mixed cellulose ester membranes are composed of cellulose acetate and cellulose nitrate. These membranes are characterized by a smoother and more uniform surface than pure nitrocellulose filters.
Artikel-Nr:
(H63457.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H63457.06
Lokale Artikelnummer::
ALFAH63457.06
Beschreibung:
Fmoc-Pro-OPfp 98%
VE:
1 * 5 g
Lieferant:
Restek
Beschreibung:
Diese anwendungsspezifischen Crossbond 35% Diphenyl/65% Dimethylpolysiloxan-Säulen mit mittlerer Polarität sind ideal für Amine und andere basische Verbindungen, einschließlich Alkylamine, Diamine, Triamine, Ethanolamine und stickstoffhaltige Heterocyclen.
Lieferant:
Thermo Scientific
Beschreibung:
Kristallviolett ACS
Lieferant:
Thermo Scientific
Beschreibung:
Ethylbromdifluoracetat
Artikel-Nr:
(PRSI25-522)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-522
Lokale Artikelnummer::
PRSI25-522
Beschreibung:
UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
VE:
1 * 50 µG
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 9000-69-5
Lieferant:
Restek
Beschreibung:
Separations of more than one hundred chiral compounds have been achieved using our unique DEX columns, and DEX columns continue to demonstrate stability after hundreds of temperature program cycles. 2,3-di-O-methyl-6-O-tert-butyl dimethylsilyl beta cyclodextrin added into 14% cyanopropylphenyl/86% dimethyl polysiloxane.These are excellent column for most chiral compounds in essential oils.
Lieferant:
Biotium
Beschreibung:
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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